“…An e-cigarette based vapor inhalation system (La Jolla Alcohol Research, Inc) which has previously been shown to deliver active doses of THC, cannabidiol, heroin, oxycodone, methamphetamine and nicotine (Gutierrez, Creehan and Taffe, 2021; Javadi-Paydar et al, 2019a; Javadi-Paydar et al, 2019b; Nguyen et al, 2016a; Nguyen et al, 2019) was used for these studies. Vapor was delivered into sealed vapor exposure chambers (152 mm W X 178 mm H X 330 mm L; La Jolla Alcohol Research, Inc, La Jolla, CA, USA) through the use of e-vape controllers (Model SSV-3 or SVS-200; 58 watts, 0.24-0.26 ohms, 3.95-4.3 volts, ∼214 °F; La Jolla Alcohol Research, Inc, La Jolla, CA, USA) to trigger SMOK Baby Beast Brother TFV8 sub-ohm tanks.…”