A Validated Potentiometric titration method for Quantitative Determination of Isoxsuprine hydrochloride from Pharmaceutical Preparation

Rajan, V Rele; Prathamesh, P Tiwatane

doi:10.5958/0974-4150.2020.00082.6

Search citation statements

Order By: Relevance

Paper Sections

Select...

Figure 2 Chemical Structure Of Isoxuprine1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various analytical methods and techniques have been used to determine the above salbutamol, and isoxsuprine, in pure form and pharmaceutical dosage including spectrophotometric 6-9 , electrochemical techniques [10][11][12][13][14] and HPLC methods [15][16][17][18] . The aim of the present work is to develop a very simple, rapid, accurate, precise, sensitive and less time consuming quantitative determination of salbutamol and isoxsuprine in pure form and pharmaceutical dosage.…”

Section: Figure 2 Chemical Structure Of Isoxuprinementioning

confidence: 99%

Spectrophotometric Determination of Salbutamol Sulphate and Isoxsuprine Hydrochloride in Pharmaceutical Formulations

2023

View full text Add to dashboard Cite

A simple, sensitive and accurate spectrophotometric method has been developed for the determination of salbutamol sulphate (SAB) and isoxsuprine hydrochloride (ISX) in pure and pharmaceutical dosage. The method involved oxidation of (SAB) and (ISX) with a known excess of N-bromosuccinamid in acidic medium, and subsequent occupation of unreacted oxidant in decolorization of Evans blue dye (EB). This, in the presence of SAB or ISX was rectilinear over the ranges 1.0-12.0, 1.0-11.0 µg/mL, with molar absorptivity 4.21×10 4 and 2.58×10 4 l.mol -1 .cm -1 respectively. The developed method had been successfully applied for the determination of the studied drugs in their pharmaceutical dosage resulting in a good agreement with certified value and standard addition procedure.

show abstract