A unique presentation of papulonodular secondary syphilis in an elderly patient

Correia, Catarina; Mendes, Rita; Sanches, Maria; Fernandes, Sónia; Soares‐Almeida, Luís; Borges‐Costa, João; Filipe, Paulo

doi:10.1111/ijd.15548

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…Hair, Nail and Teeth were normal. Differentials for annular secondary syphilis, depending on anatomic site and clinical scenario, include dermatophytosis [14][17][19], er ythema annulare centrifugum [4][21], Annular lichen planus, Annular Psoriasis, subacute cutaneous lupus erythematosus, sarcoidosis, atypical mycobacterial infection [6] and granuloma annulare [5]. On routine investigation like CBP, HBSAG, HIV, HBCG were normal, Fungal scrapings were negative and VDRL was positive with specific TPHA showing 1:640 dilution.…”

Section: Case Reportmentioning

confidence: 99%

A Case Report of Annular Palmoplantar Syphils in This Post Covid 19 Antibiotic Era

Nikhat,

Meher

2023

PIJR

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Syphilis is an age old major sexually transmitted disease caused by treponema pallidum which can't be forgotten in the differential diagnosis even in this 21st century of wide antibiotics usage era specially in the post covid 19times. Conclusion Syphilis shows a good response to penicillin treatment and requires vigilance on the part of practitioners. We are reporting a High Index of suspicion arises with atypical clinical manifestations, Specific localized atypical, almost rare form of annular syphilis case in a world of widely antibiotic usage era mostly post covid 19. Henceforth all the healthcare providers should be consulted by public health professionals who are following up on a patient with a positive syphilis (or other Sexually Transmitted Infections) case. Dermatologists play an important role in the recognition and management of syphilis. Timely diagnosis, appropriate management as well as public health interventions are key in controlling syphilis infection and its spread. Finally, Annular secondary syphilis has a good response to penicillin treatment. Aim Early diagnosis of syphilis is vital as it is easily treated in its early stages with a single dose of benzathine penicillin. Timely and effective treatment of early syphilis is important to prevent onward transmission and progression to tertiary syphilis or the mucocutaneous lesions of secondary syphilis (“syphilids”). Objectives Syphilis cases should be reported by stage to the local or state health department as soon as possible Background Syphilis is an infection caused by Treponema pallidum, mainly transmitted by sexual contact [1]. Since 2001, primary and secondary syphilis rates started to rise, with an epidemic resurgence. Syphilis is global prevalence and incidence remain high in post COVID19. It is divided into primary syphilis, secondary syphilis, tertiary syphilis, and neurosyphilis. Its florid presentation renders the name “the great imitator” great mimicker “Lues” “THE GREAT POX” [2]

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Section: Case Reportmentioning

confidence: 99%

A Case Report of Annular Palmoplantar Syphils in This Post Covid 19 Antibiotic Era

Nikhat,

Meher

2023

PIJR

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“…The clinical protocol and therapeutic guidelines for sexually transmitted infections 5 recommend the use of benzathine benzylpenicillin 2.4 million international units (IU), intramuscularly (IM), in a single-dose (1.2 million in each gluteus). However, most treated cases report a better outcome with the administration of three doses 6 , 7 . The dermatologist, in this case, chose to treat the suggestive secondary syphilis with benzathine penicillin and a total dose of 4,800,000 IU as a precaution.…”

Section: Case Reportmentioning

confidence: 99%

Atypical presentation of secondary syphilis: annular lesions in an elderly patient

Pagani

Pacheco

Venier

et al. 2021

Rev. Inst. Med. trop. S. Paulo

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Syphilis is a chronic bacterial sexually transmitted infectious disease caused by Treponema pallidum . Different age groups are affected by heterogeneous clinical forms of the disease. We report a case of atypical secondary syphilis in an elderly patient with diffuse annular erythematous lesions on the chest, back, upper and lower limbs diagnosed by histopathological, immunohistochemical and serological tests.

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A unique presentation of papulonodular secondary syphilis in an elderly patient

Cited by 2 publications

References 5 publications

A Case Report of Annular Palmoplantar Syphils in This Post Covid 19 Antibiotic Era

A Case Report of Annular Palmoplantar Syphils in This Post Covid 19 Antibiotic Era

Atypical presentation of secondary syphilis: annular lesions in an elderly patient

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