A Unique Pattern of Hyperhidrosis and Herpes Zoster

Localized crossed hyperhidrosis and the coexistence of thyroid gland disease

“…Some forms of localized hyperhidrosis manifest solely on one side of the body and are called “unilateral localized hyperhidrosis”. These cases may have underlying tumors including bronchogenic carcinomas, mesotheliomas or neurological disorders such as cerebral infarction, spinal cord injuries and compression of a nerve root due to spinal tumors, dysfunction of autonomic nerve system 3–8,13–15 . However, this disorder occasionally occurs in healthy people with no reason; thus, these cases are called “idiopathic unilateral localized hyperhidrosis”.…”

“…Intrathoracic tumors, especially mesotheliomas involving the sympathetic trunk or postganglionic sympathetic fibers, can also cause ipsilateral paroxysmal hyperhidrosis or multisegmental hyperhidrosis along particular dermatomes 14 . Similarly, neurological sequelae developed after herpes zoster infection may be a plausible putative mechanism for dermatomal hyperhidrosis 15 . However, both past medical history of the patient and serological test for VZV immunoglobulin G were negative.…”

“…These cases may have underlying tumors including bronchogenic carcinomas, mesotheliomas or neurological disorders such as cerebral infarction, spinal cord injuries and compression of a nerve root due to spinal tumors, dysfunction of autonomic nerve system. [3][4][5][6][7][8][13][14][15] However, this disorder occasionally occurs in healthy people with no reason; thus, these cases are called ''idiopathic unilateral localized hyperhidrosis''. Autonomic dysregulation has been proposed in the cases where no reason was found in investigations.…”

“…Localized hyperhydrosis (LH) occurring symmetrically on the palms, soles and/or armpits is an ordinary and idiopathic disorder which represents a complex dysfunction of the autonomic nervous system 1,2 . It occurs very rarely on the body unilaterally or lesionally 3–17 . Occasionally, a craniofacial involvement occurs secondary to selective serotonin reuptake blockers 18 .…”

“…1,2 It occurs very rarely on the body unilaterally or lesionally. [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] Occasionally, a craniofacial involvement occurs secondary to selective serotonin reuptake blockers. 18 These situations are different from eccrine nevi because of the existence of normal eccrine glands in the sweating areas.…”