The pollutants from the environment are absorbed by wet deposition which increases the pollutants transport. To create and produce different substances, the constituent atoms of the reactants should be rearranged by the chemical reaction. The introduced theoretical model demonstrate the dispersal of pollutants inherited from point and line source without and with both wet deposition and chemical reaction, respectively. The advection-diffusion equation is solved. Taking the wind speed is a function of downwind distance, lateral eddy diffusivity is a function of wind speed and vertical eddy diffusivity is a function of both wind speed and vertical height of power “z”. In this paper the variable separable method and Hankel transform are used to get the concentration from point and line source. Predicted concentration of pollutants in unstable condition is done. Variation concentrations of both observed and predicted of radioactive Iodine135 (I-135), inside Research Reactor at Inshas Egyptian Atomic Energy Authority, in unstable condition is shown without chemical reaction and wet deposition. It is discovered that the proposed model is a good harmony with observed concentrations data and the proposed data inside a factor of two. Also, studying the effect of wet deposition and chemical reaction on concentration of air contaminants of line source is analysed.