A tutorial on asymmetric electrocatalysis

Abstract

This tutorial review delves into the unique advantages of electrochemistry in the context of asymmetric catalysis, first providing a brief tutorial introduction to electrosynthesis, then exploring representative case studies with a mechanistic focus.

Overview of Recent Scale-Ups in Organic Electrosynthesis (2000–2023)

“…A range of additional transformations are emerging as opportunities toward scalable processes (e.g., electrochemical trifluoromethylation of heterocycles, hydrogenations − ) that may be of high interest to pharma. The electrosynthesis of catalysts , and ligands , for catalysis and the deployment of asymmetric electrocatalytic methods are also of interest, but examples of these on large scale are still scarce. The development of electrosynthetic processes in green solvents is also of interest.…”

Recent advances in oxidative degradation of plastics

“…Other than those listed above, there are many other advantages of using electricity as a stimulus in organic synthesis (see these reviews for more details). 157–159 Typical electrochemical reactions consist of two simultaneous redox half-reactions, which are both happening at the electrode surface. Oxidation (removing electrons) occurs at the anode, while reduction (gaining electrons) occurs at the cathode (Fig.…”

When transition-metal catalysis meets electrosynthesis: a recent update

“…23 The concept of metalla-electrocatalysis for enantioselective synthesis has been reviewed before and is not covered in this review. 24,25 In addition, transition-metal catalysis under electrophotochemical conditions is also excluded from this review because it represents another domain of organic synthesis. [26][27][28][29][30][31][32] The current review is organized based on metal catalysts, with specific focus placed on strategy design and mechanistic aspects.…”