“…The concentration of copper ions may be extremely low in the presence of organic matter, and high when the ligand is insufficient. However, trace amount of Cu 2+ has been detected in food samples, living zebrafish (Zhou et al., 2021 ), and AD rat brains (Yu et al., 2017 ) and significant toxicity was found. The toxicity of copper ions has been well established by a lot of articles.…”
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
“…The concentration of copper ions may be extremely low in the presence of organic matter, and high when the ligand is insufficient. However, trace amount of Cu 2+ has been detected in food samples, living zebrafish (Zhou et al., 2021 ), and AD rat brains (Yu et al., 2017 ) and significant toxicity was found. The toxicity of copper ions has been well established by a lot of articles.…”
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
“…12,13 These factors have contributed to great attention devoted to fluorescent sensors in comparison with other sensing methods. [14][15][16][17][18][19][20][21] Metal-mediated base-paired DNA (in the form of aptamers or oligonucleotides) has long been scrutinized in basic scientific research and for the purposes of fluorescence biosensing applications. Oligonucleotides, having a strong interaction capability with specific metal ions, are well suited to the creation of a fluorometric biosensor due to the ease of tagging fluorophores at precise positions, binding-induced changes in oligonucleotide structures, hybridization of the oligonucleotides to complementary oligonucleotide sequences, changes in molecular volume upon the binding interaction of oligonucleotides with their target (metal ions or biomolecules), and adsorption of oligonucleotides onto quenching nanomaterials.…”
Increased levels of toxic metal/non-metal ions Cadmium (Cd2+) and Sulfide (S2−) in the environment can be detrimental to human health. Given the circumstances, the detection and measurement of Cd2+ and...
“…Compared with nanomaterials, organic chemical probes are of superior biocompatibility, flexible structural modification and relatively low toxicity. In addition, fluorescence bioimaging technology allows us to detect a variety of metal ions including Cu(II) in vivo at a subcellular level [22,23], thus they were receiving much more attention.…”
Background: Abnormal Cu(II) ions levels may affect many biological functions, and it is of great importance to detect Cu(II) ions in organisms. Methods: Herein, we report a near-infrared (NIR) fluorescent probe EtRh-N-NH2 for the detection of Cu(II). In the probe structure, a rhodamine core was used, and a hydrazine group was employed as the responsive site. Results & Conlusions: EtRh-N-NH2 displayed sensitive, specific and fast response upon Cu(II) with excellent linear relationship between the concentration and fluorescence emission intensity in 0-1 µM range. The releasing EtRh-COOH exhibited 762 nm of emission wavelength with a 75 nm of Stokes shift.
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