A turn-on green channel Zn2+ sensor and the resulting zinc(<scp>ii</scp>) complex as a red channel HPO42− ion sensor: a new approach

Lohar, Somenath; Pal, Siddhartha; Mukherjee, Manjira; Maji, Abhishek; Demitri, Nicola; Chattopadhyay, Pabitra

doi:10.1039/c7ra02175e

Cited by 41 publications

(12 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the fluorescence changes influenced by Zn 2+ ion exhibits good linear relationships (Figure S8), which means that the probe PIS is very much suitable for quantitative recognition of Zn 2+ ion. Afterwards, the limit of detection (LOD) was calculated (using formula LOD=3σ/K) and found to be 0.52 nM, which is lower than most of the previously reported DFP fluorophore based zinc sensors . Moreover, the association or binding constant for PIS‐Zn 2+ ensemble ( K b = 2.36 x 10 6 M −1 ) was calculated from fluorescence titration experiments by Benesi‐Hildebrand equation (Figure S9).…”

Section: Resultsmentioning

confidence: 94%

“…Our synthesized probe PIS was compared with the already reported DFP based Schiff base chemosensors towards zinc and pyrophosphate ion detection . Although the reported chemosenors have some advantages such as easy synthesis, sensitivity of detection and practical application, the present chemosensor PIS have some advantages like low detection limit, high binding constant, naked eye detection, higher excitation wavelength in the visible region and no interference from other ions.…”

Section: Resultsmentioning

confidence: 99%

“…In this direction, recent years, attention has been diverted to a new fluorophore, namely 4‐methyl‐2,6‐diformylphenol (DFP) which gives a dual fluorescence emission both in solution or in the solid state due to its high fluorescence nature. Furthermore, on the basis of interesting properties of DFP, researchers have been established various chemosensors by using DFP as fluorophore, for the detection of Zn 2+ ion …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Simple Perceptive Diphenyl‐Imidazole‐Based Dipodal Schiff‐Base Chemosensor for Zn²⁺ and PPi ions and Its Live‐Cell Imaging Applications

et al. 2018

View full text Add to dashboard Cite

2,6-bis((E)- (2-(benzo[d]thiazol-2-yl)hydrazono)methyl)-4-(4,5-diphenyl-1H-imidazol-2-yl)phenol (PIS) conjugate has been designed as a selective fluorescent probe for zinc ion. The PIS exhibits selectivity towards Zn 2 + among various ions in DMSO-H 2 O (1:9) v/v 50 mM HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) at pH = 7.4. Moreover, the detection of PIS towards Zn 2 + ion could be realized in " naked eye" with a color conversion from yellow to greenish yellow. The linear relationship between fluorescence intensity and Zn 2 + ion concentration indicates that PIS can be used for quantification of Zn 2 + ion. The PIS probe can be used in broad pH ranging from 4 to 9. The limit of detection (LOD) was found to be 0.52 nM for Zn 2 + ion. The binding ratio and binding constant of PIS-Zn 2 + complex were determined and calculated as 1:1 and 2.36 × 10 6 M À 1 according to Job's plot and Benesi-Hildebrand equation, respectively. Furthermore, the PIS-Zn 2 + complex subsequently acted as a secondary fluorescent turn-off probe for pyrophosphate (PPi) ion recognition among the other anions. To assess the real-world efficacy of the PIS and PIS-Zn 2 + complex, they were evaluated by test paper strips. Likewise, the probe PIS and PIS-Zn 2 + complex were used as in vitro cell imaging probe, and successfully demonstrated as feasible biomarker as well.

show abstract

Section: Resultsmentioning

confidence: 94%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Simple Perceptive Diphenyl‐Imidazole‐Based Dipodal Schiff‐Base Chemosensor for Zn²⁺ and PPi ions and Its Live‐Cell Imaging Applications

et al. 2018

View full text Add to dashboard Cite

show abstract

“…In this context, fluorescent chemosensors for cyanide ions are significantly attractive because of low cost and present numerous advantages, including high sensitivity and easy operation. 28 , 29 …”

Section: Introductionmentioning

confidence: 99%

Highly Sensitive Ratiometric Chemosensor and Biomarker for Cyanide Ions in the Aqueous Medium

Lohar

Dhara²,

Roy

et al. 2018

ACS Omega

Self Cite

View full text Add to dashboard Cite

A newly designed cyanide-selective chemosensor based on chromone containing benzothiazole groups [3-(2,3-dihydro-benzothiazol-2-yl)-chromen-4-one (DBTC)] was synthesized and structurally characterized by physico-chemical, spectroscopic, and single-crystal X-ray diffraction analyses. The compound DBTC can detect cyanide anions based on nucleophilic addition as low as 5.76 nM in dimethyl sulfoxide–N-(2-hydroxyethyl)piperazine-N′-ethanesulfonic acid buffer (20 mM, pH 7.4) (v/v = 1:3). The binding mode between receptor DBTC and cyanide nucleophile has also been demonstrated by experimental studies using various spectroscopic tools and theoretical studies, and the experimental work has also been verified by characterizing one supporting compound of similar probable structure of the final product formed between DBTC and cyanide ion (DBTC–CN compound) by single-crystal X-ray analysis for detailed structural analyses. In theoretical study, density functional theory procedures have been used to calculate the molecular structure and the calculation of the Fukui function for evaluation of the electrophilic properties of each individual acceptor atom. Furthermore, the efficacy of the probe (DBTC) to detect the distribution of CN– ions in living cells has been checked by acquiring the fluorescence image using a confocal microscope. Notably, the paper strips with DBTC were prepared, and these could serve as efficient and suitable CN– test kits successfully.

show abstract

“…It is known that 2,6‐diformyl‐4‐methyl‐phenol has unique advantages among other fluorophores owing to its excellent photophysical properties, such as visible absorption, high fluorescence quantum yield, good photostability, and water solubility, was used previously as a sensor system by our group …”

Section: Introductionmentioning

confidence: 99%

A Highly Selective Fluorescence Turn‐On Probe for the Sensing and Bioimaging of Hypochlorite Anion in Aqueous Media

et al. 2018

Self Cite

View full text Add to dashboard Cite

A newly designed and structurally characterized 2,6-diformyl À4-methyl-phenol based moiety detects the hypochlorite ions as low as 75.9 nM selectively in DMSO-H 2 O (1:9, v/v) solution (100 mM HEPES buffer, pH 7.4) based on oxidation cleavage reaction of the thioacetal linkage. To establish this reaction based pathway in favor of sensing hypochlorite ions, the detailed spectroscopic studies have been carried out systematically supported by theoretical (DFT) studies. The efficacy of this non-cytotoxic probe has been checked by acquiring the fluorescence images of the distribution of the hypochlorite (ClO À ) ion in living cells.

show abstract

A turn-on green channel Zn²⁺ sensor and the resulting zinc(ii) complex as a red channel HPO₄²⁻ ion sensor: a new approach

Abstract: A turn-on green channel Zn2+ sensor and the resulting zinc(ii) complex as a red channel HPO42− ion sensor: a new approach.

Cited by 41 publications

References 76 publications

A Simple Perceptive Diphenyl‐Imidazole‐Based Dipodal Schiff‐Base Chemosensor for Zn²⁺ and PPi ions and Its Live‐Cell Imaging Applications

A Simple Perceptive Diphenyl‐Imidazole‐Based Dipodal Schiff‐Base Chemosensor for Zn²⁺ and PPi ions and Its Live‐Cell Imaging Applications

Highly Sensitive Ratiometric Chemosensor and Biomarker for Cyanide Ions in the Aqueous Medium

A Highly Selective Fluorescence Turn‐On Probe for the Sensing and Bioimaging of Hypochlorite Anion in Aqueous Media

Contact Info

Product

Resources

About

A turn-on green channel Zn2+ sensor and the resulting zinc(ii) complex as a red channel HPO42− ion sensor: a new approach

Abstract: A turn-on green channel Zn2+ sensor and the resulting zinc(ii) complex as a red channel HPO42− ion sensor: a new approach.

Cited by 41 publications

References 76 publications

A Simple Perceptive Diphenyl‐Imidazole‐Based Dipodal Schiff‐Base Chemosensor for Zn2+ and PPi ions and Its Live‐Cell Imaging Applications

A Simple Perceptive Diphenyl‐Imidazole‐Based Dipodal Schiff‐Base Chemosensor for Zn2+ and PPi ions and Its Live‐Cell Imaging Applications

Highly Sensitive Ratiometric Chemosensor and Biomarker for Cyanide Ions in the Aqueous Medium

A Highly Selective Fluorescence Turn‐On Probe for the Sensing and Bioimaging of Hypochlorite Anion in Aqueous Media

Contact Info

Product

Resources

About

A turn-on green channel Zn²⁺ sensor and the resulting zinc(ii) complex as a red channel HPO₄²⁻ ion sensor: a new approach

A Simple Perceptive Diphenyl‐Imidazole‐Based Dipodal Schiff‐Base Chemosensor for Zn²⁺ and PPi ions and Its Live‐Cell Imaging Applications

A Simple Perceptive Diphenyl‐Imidazole‐Based Dipodal Schiff‐Base Chemosensor for Zn²⁺ and PPi ions and Its Live‐Cell Imaging Applications