A “turn-on” fluorescent probe for glutathione detection based on the polyethylenimine-carbon dots-Cu2+ system

Zhang, Boye; Duan, Qianqian; Li, Yi; Zhang, Yixia; Che, Mingxuan; Zhang, Wendong; Sang, Shengbo

doi:10.1016/j.jphotobiol.2019.111532

Cited by 28 publications

(15 citation statements)

References 26 publications

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“…Sang and colleagues recently developed a "turn-on" fluorescent sensor for GSH detection based on a PEI-CDs/ Cu 2+ system. 103 PEI-CDs displayed a strong fluorescence emission at around 480 nm, while the fluorescence intensity significantly decreased after binding with Cu 2+ due to the interaction between surface amine groups of PEI-CDs and Cu 2+ . Since the binding efficacy between Cu 2+ and PEI-CDs was much lower relative to that between Cu 2+ and GSH, PEI-CDs were released from PEI-CDs/Cu 2+ system upon the addition of GSH to recover their fluorescence emission (Figure 6a).…”

Section: Biosensing Of Metal Ionsmentioning

confidence: 99%

“…Sang and colleagues recently developed a “turn-on” fluorescent sensor for GSH detection based on a PEI-CDs/Cu 2+ system . PEI-CDs displayed a strong fluorescence emission at around 480 nm, while the fluorescence intensity significantly decreased after binding with Cu 2+ due to the interaction between surface amine groups of PEI-CDs and Cu 2+ .…”

Section: Biosensing Of Various Bioanalytesmentioning

confidence: 99%

Section: Biosensing Of Various Bioanalytesmentioning

confidence: 99%

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Polyethylenimine-Assisted Generation of Optical Nanoprobes for Biosensing Applications

Wang

Shen

et al. 2020

ACS Appl. Bio Mater.

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Detection of analytes in biological systems is pivotal to explore their physiological roles and provide diagnostic and treatment options for related diseases, which however remains a great challenge. Optical nanoprobes that exhibit absorption or fluorescence signal changes in response to the targets of interest have emerged as a versatile class of biosensors in the field. Polyethylenimine (PEI) with abundant amine groups plays indispensable roles in the construction of optical nanoprobes and mediating the sensing processes. After interaction with analytes, PEI-based optical nanoprobes can be induced to form aggregates, be disassembled or separated into individual units, or undergo structure/component alterations. As such, the optical properties of these nanoprobes have corresponding changes, allowing for sensitive and selective detection of a wide variety of analytes in biological environment. Up to now, detections of reactive oxygen species, pH, metal ions, biothiols, neurotransmitters, therapeutic agents, oxygen levels, enzyme activities, and virus/bacteria have been successfully demonstrated using PEI-based optical nanoprobes. Herein, we summarize the recent developments of PEI-based optical nanoprobes for biosensing applications and highlight the probe designs and sensing mechanisms. The existing challenges and prospects regarding biosensing applications of PEI-based optical nanoprobes are also briefly discussed.

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Section: Biosensing Of Metal Ionsmentioning

confidence: 99%

Section: Biosensing Of Various Bioanalytesmentioning

confidence: 99%

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Polyethylenimine-Assisted Generation of Optical Nanoprobes for Biosensing Applications

Wang

Shen

et al. 2020

ACS Appl. Bio Mater.

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“…Owing to their low cytotoxicity, small size, and admirable biocompatibility, carbon dots (CDs) have unveiled a novel perspective for the recognition of GSH. , Yang et al designed fluorescent CDs for the simultaneous detection of Hg 2+ and GSH in biological samples. Zhang et al developed a PEI–CD–Cu 2+ system for discriminating GSH based on its strong binding ability with Cu 2+ . Yan et al reported fluorescent yellow-emissive CDs for the sequential determination of Ag + and GSH.…”

Section: Introductionmentioning

confidence: 99%

“…16,17 Yang et al 18 designed fluorescent CDs for the simultaneous detection of Hg 2+ and GSH in biological samples. Zhang et al 19 developed a PEI−CD−Cu 2+ system for discriminating GSH based on its strong binding ability with Cu 2+ . Yan et al 20 reported fluorescent yellow-emissive CDs for the sequential determination of Ag + and GSH.…”

Section: Introductionmentioning

confidence: 99%

Dual Photoluminescence Emission Carbon Dots for Ratiometric Fluorescent GSH Sensing and Cancer Cell Recognition

Shi

Jia

et al. 2020

ACS Appl. Mater. Interfaces

131

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We developed a facile strategy for the fabrication of dual-emission carbon nanodots (CDs) and demonstrated their applications for ratiometric glutathione (GSH) sensing and for differentiating cancer cells from normal cells. Dual-emission CDs were synthesized using a simple hydrothermal treatment of alizarin carmine as the carbon source, manifesting intriguing dual-emission behavior at 430 and 642 nm. With increasing GSH concentration, the fluorescence band at 430 nm increased gradually, whereas that at 642 nm decreased slightly. With monitoring of the intrinsic ratiometric fluorescence variation (I 430nm/I 642nm), as-prepared CDs were developed as an effective platform for ratiometric fluorescent GSH sensing, with a linear range of 1–10 to 25–150 μM and a detection limit of 0.26 μM. More importantly, confocal fluorescent imaging of cancer cells and normal cells indicated that obtained CDs could be implemented as an effective tool to visualize cancer cells with overexpressing GSH.

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Effect of BN or B₄C content on physical and tribological properties of copper‐clad laminates reinforced with carbon fiber and epoxy resin

Sang,

Liang

2024

J of Applied Polymer Sci

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Plasma treatment was used to improve the surface roughness of copper foil. The copper‐clad laminates reinforced with carbon fiber, boron nitride (BN), or boron carbide (B4C), and epoxy resin were prepared by hot pressing. The effect of BN or B4C content on the physical properties and tribological properties of copper‐clad laminates reinforced with carbon fiber and epoxy resin were studied. The resulting copper‐clad laminate exhibited desirable properties, such as dielectric constant, peel strength, oxygen index, and arc resistance, which were influenced by the concentration of BN or B4C particles. Additionally, the wear and friction properties of the laminate were evaluated, revealing the effects of load, sliding speed, and particle content on weight loss, specific wear rate, and coefficient of friction. SEM analysis of worn surfaces provided insight into the stages of wear, highlighting the importance of an oxide layer in reducing wear and protecting the copper surface.

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A “turn-on” fluorescent probe for glutathione detection based on the polyethylenimine-carbon dots-Cu2+ system

Cited by 28 publications

References 26 publications

Polyethylenimine-Assisted Generation of Optical Nanoprobes for Biosensing Applications

Polyethylenimine-Assisted Generation of Optical Nanoprobes for Biosensing Applications

Dual Photoluminescence Emission Carbon Dots for Ratiometric Fluorescent GSH Sensing and Cancer Cell Recognition

Effect of BN or B₄C content on physical and tribological properties of copper‐clad laminates reinforced with carbon fiber and epoxy resin

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A “turn-on” fluorescent probe for glutathione detection based on the polyethylenimine-carbon dots-Cu2+ system

Cited by 28 publications

References 26 publications

Polyethylenimine-Assisted Generation of Optical Nanoprobes for Biosensing Applications

Polyethylenimine-Assisted Generation of Optical Nanoprobes for Biosensing Applications

Dual Photoluminescence Emission Carbon Dots for Ratiometric Fluorescent GSH Sensing and Cancer Cell Recognition

Effect of BN or B4C content on physical and tribological properties of copper‐clad laminates reinforced with carbon fiber and epoxy resin

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Product

Resources

About

Effect of BN or B₄C content on physical and tribological properties of copper‐clad laminates reinforced with carbon fiber and epoxy resin