A triad of troubling findings

Plummer‐vinson Syndrome: A Report of Three Cases

“…In most cases, treatment of the iron deficiency alone rapidly improves the dysphagia. If obstruction of the lumen due to the webs persists, or webs have been present for more than two years, dilatation may be required 12,21 . Iron deficiency may be related to pica in one of our patients, and to increased flow during menses in the other, although anaemia of specific origin is not necessary for the diagnosis of the syndrome.…”

"Plummer -Vinson Syndrome: Diagnosis by Barium Esophagogram Studies May Still Be Important in the Shortage of Endoscopic Sources"

“…However, there are studies reporting that not all upper esophageal webs cause dysphagia and even a smaller fraction is associated with PVS. An influential study by Nosher, et al [16] reported upper esophageal webs, present in 5.5% of screening esophagograms, were not associated with dysphagia; and while overall incidence of iron deficiency anemia was increased in patients with upper esophageal webs, the difference was statistically insignificant [3,11,[16][17] However, the mentioned study suffers from a limitation similar to ours: Both studies cannot estimate the effect of any prior treatments to correct iron deficiency states on laboratory parameters of anemia work-up.…”

Recurrent Post Cricoid Web in Plummer Vinson Syndrome – Is It Malignancy Next?

“…PVS has been identified as a risk factor for developing squamous cell carcinoma of the upper gastrointestinal tract [13] . Three to fifteen percent of the patients with PVS, mostly women between 15-50 years of age have been reported to develop oesophageal or pharyngeal cancer [12] . According to Kim et al [15] PVS is thought to be precancerous because squamous cell carcinoma of hypo pharynx, oral cavity or oesophagus takes place in 10% of those patient suffering from this malady.…”