“…In Europe, a sex bias has been observed in trepanation techniques: the grooving technique is more common than the others in male individuals, while the scraping technique was the most used in female individuals (Campillo, 2007). Female cases of trepanation have been found even in very ancient times (see Prioreschi, 1996), but are uncommon, as this procedure seems to have been predominantly carried out on adult males (Piggott, 1940;Campillo, 1984;Jennbert, 1991). Examples of trepanned children skulls are also very rare (Jordanov et al, 1988;Verano, 2003;Andrushko and Verano, 2008) and some authors have proposed that this probably reflects (i) the lower childhood frequency of the susceptible disorders that were treated by cranial surgery; (ii) an uneven conservancy of fragile skeletal remains; or (iii) a reluctance of ancient physicians to expose children to potentially life-threatening surgical techniques (MarianiCostantini et al, 2000).…”