A tongue resection in macroglossia due to primary amyloidosis

Dendy, R.A.; Davies, J. R.; Gorst, D. W.

doi:10.1016/0266-4356(89)90047-8

Cited by 12 publications

(3 citation statements)

References 3 publications

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“…Since multiple myeloma is a malignant neoplasm and development of primary amyloidosis shortens the survival, noninvasive and conservative treatments are primarily recommended for localized lesions, but surgical interventions can be inevitable for severe cases with extensive lesions compromising vital functions (1,13,14). In our case, we preferred to follow-up our patient since the lesions were not hindering vital functions.…”

Section: Riscussionmentioning

confidence: 99%

A Case of Multiple Myeloma and Amyloidosis of the Tongue

Şanlı¹

2005

Journal of Ankara Medical School

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Section: Riscussionmentioning

confidence: 99%

A Case of Multiple Myeloma and Amyloidosis of the Tongue

Şanlı¹

2005

Journal of Ankara Medical School

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“…In cases of progressive macroglossia, surgical reduction can improve complications of deglutition, respiration, cosmetic appearance, and patient comfort. 21 In the setting of systemic amyloidosis, the macroglossia is likely to recur if the underlying plasma cell dyscrasia is not medically controlled. 22 Although treatment for localized disease is primarily surgical, observation can be undertaken, particularly if the mass is asymptomatic.…”

Section: Discussionmentioning

confidence: 99%

Localized Tongue Amyloidosis: A Single Institutional Case Series

O’Reilly

D’Souza

Lust

et al. 2013

Otolaryngol.--head neck surg.

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“…Partial resection of the tongue has been undertaken for macroglossia, partic ularly when stridor develops [ 103], but is dan gerous due to bleeding and tracheostomy may be preferable. In achalasia due to amyloid, pneumatic dilatation of the esophagus has been effective [30].…”

Section: Therapy For the Gastrointestinal Tractmentioning

confidence: 99%

Amyloid and the Gut

Lovat

Pepys

Hawkins

1997

Dig Dis

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The systemic amyloidoses are serious and potentially fatal disorders caused by deposition of autologous proteins in an abnormal fibrilllar from. The clinical features are highly variable but gut involvement is common and random gastrointestinal biopsies are diagnostic in 80% of patients. Presentations include macroglossia, motility disorders, hemorrhage and pseudo-tumors, although amyloid can mimic almost any other gut pathology. Nonspecific mucosal abnormalities are common both radiologically and at endoscopy. Scintigraphy with serum amyloid P component demonstrates and quantifies the systemic amyloid deposits. Therapy that reduces the supply of the amyloid fibril precursor protein can markedly improve prognosis. Intensive nutritional support for malnourished patients, motility-enhancing drugs and octretide for motility disorders, and correction of clotting disorders in bleeding patients are important adjunctive treatments.

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A tongue resection in macroglossia due to primary amyloidosis

Cited by 12 publications

References 3 publications

A Case of Multiple Myeloma and Amyloidosis of the Tongue

A Case of Multiple Myeloma and Amyloidosis of the Tongue

Localized Tongue Amyloidosis: A Single Institutional Case Series

Amyloid and the Gut

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