A Ten-Year Study of Drug Poisoning Cases Admitted to the Intensive Care Unit of 5 Azar Hospital in Gorgan, Iran

Shokrzadeh, Mohammad; Hoseinpoor, Reza; Jafari, Danial; Delaram, Azam; Sadr, Akram Pouyan; Deylami, Mehrnoosh; Shayeste, Yaghoub

doi:10.29252/jcbr.3.2.8

Cited by 3 publications

(7 citation statements)

References 9 publications

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“…Over‐the‐counter (OTC) access to benzodiazepines appears to play a major role in drug intoxication in the study population. Numerous studies have been performed in this regard in the past, and their findings are consistent with the findings of the present study 20,25,27,32 …”

Section: Discussionsupporting

confidence: 93%

“…In this study, poisoning with drugs such as benzodiazepines and methadone was the most common cause of poisoning during 2012–2018. The mean age of poisoning in men and women has decreased, and these findings are consistent with the findings of other studies conducted in Iran and other countries 17,20,21,25–28 . The prevalence of poisoning in young people can be due to socioeconomic conditions.…”

Section: Discussionsupporting

confidence: 90%

“…The mean age of poisoning in men and women has decreased, and these findings are consistent with the findings of other studies conducted in Iran and other countries. 17,20,21,[25][26][27][28] The prevalence of poisoning in young people can be due to socioeconomic conditions. This suggests that psychological interventions and the development of life skills can be very useful in reducing the prevalence of poisoning in young people.…”

Section: Discussionmentioning

confidence: 99%

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The trend of top five types of poisonings in hospitalized patients based on ICD‐10 in the northeast of Iran during 2012–2018: A cross‐sectional study

Yazdipour

Moshiri

Dadpour

et al. 2022

Health Science Reports

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Background and Aims: Poisoning remains a major health issue in developing countries with high morbidity and mortality rates; also it is one of the most common causes of admission to hospitals. This study aimed to investigate the trend of the top five types of poisonings in hospitalized patients according to the International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) in Imam Reza hospital, Mashhad, Iran.Methods: This was a cross-sectional study performed from March 20, 2012, until September 22, 2018. We collected data from all patients hospitalized for poisoning admitted to the poisoning center at Imam Reza hospital in northeast Iran. ICD-10 was adopted to categorize all types of poisonings (T36-T65). The results obtained were analyzed by SPSS 16.Results: Thirty-four thousand eight hundred and ten cases were included. The mean age of the patients was 29.64 ± 14.69 years, of them, 50.7% were males.Benzodiazepine poisoning (T42.4) has the highest frequency among other subcategories and it was more common among females (60.5%). Opium poisoning (T40.0) has the highest mortality rate (5.4%) among other subcategories that is more common in males (72.0%). The mortality associated with narcotics was the highest frequency (2.7%). Suicide (83.6%) was the most common cause of poisoning. Most poisonings occurred in summer (27.4%). Conclusion:These findings could help health care managers and policymakers develop prevention and educational programs to reduce these poisonings and limit people's easy access to drugs and substances.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The trend of top five types of poisonings in hospitalized patients based on ICD‐10 in the northeast of Iran during 2012–2018: A cross‐sectional study

Yazdipour

Moshiri

Dadpour

et al. 2022

Health Science Reports

View full text Add to dashboard Cite

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“…Alternatively, pharmaceutical medications and opioids represented most ICU admitted acutely poisoned patients in Turkey 41 and Western countries 1 . This difference is attributed to the geographical accessibility of these chemicals/drugs 42 …”

Section: Discussionmentioning

confidence: 99%

Development of a risk prediction nomogram for disposition of acute toxic exposure patients to intensive care unit

Elgazzar

Afifi

Shama

et al. 2021

Basic Clin Pharma Tox

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Early risk stratification of acutely poisoned patients is essential to identify patients at high risk of intensive care unit (ICU) admission. We aimed to develop a prognostic model and risk‐stratification nomogram based on the readily accessible clinical and laboratory predictors on admission for the probability of ICU admission in acutely poisoned patients. This retrospective cohort study included adult patients with acute toxic exposure to a drug or a chemical substance. Patients' demographic, toxicologic, clinical and laboratory data were collected. Among the 1260 eligible patients, 180 (14.3%) were admitted to the ICU. We developed a generalized prognostic model for predicting ICU admission in patients with acute poisoning. The predictors included the Glasgow coma scale, oxygen saturation, diastolic blood pressure, respiratory rate and blood bicarbonate concentration. The model displayed excellent discrimination and calibration (optimistic‐adjusted area under the curve = 0.924 and optimistic‐adjusted Hosmer and Lemeshow test = 0.922, respectively) when internally validated. Additionally, we developed prognostic models that determine ICU admission in patients with specific poisonings. Furthermore, we constructed risk‐stratification nomograms that rank the probability of ICU admission in these patients. The developed risk‐stratification nomograms help decision‐making regarding ICU admission in acute poisonings. Future external validation in independent cohorts is necessary before clinical application.

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“…In the study about the causes of coma in patients who were admitted to poisoning ICU, 18.6% of patients were expired [17]. Also, the mortality rate of patients admitted to poisoning ICU was reported at 4.1% and 6.1% in other studies [18,19].…”

Section: Discussionmentioning

confidence: 99%

Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning

Soltaninejad

Beigi

Golshiri

et al. 2021

IJMTFM

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Background: Patients with acute poisoning sometimes require hospitalization in the Intensive Care Unit (ICU). The correct admission of these patients has resulted to lower mortality. This study compared the characteristics of adult patients with acute poisoning who were admitted to the poisoning ward and the ICU. We also determined the relevant outcome predictive factors. Methods: This cross-sectional study was conducted on adult acutely poisoned patients who were admitted to the emergency room of Khorshid Hospital affiliated with Isfahan University of Medical Sciences from October 2018 to 2019. The clinico-epidemiological variables and outcomes were compared between adult patients hospitalized in the ward (n=100) and ICU (n=100). Binary logistic regression was used for predicting the outcome factors. Results: The Mean±SE age of the study patients in the ICU and ward were 36.6±1.62 (median: 34) and 34.20±1.19 years, (median: 33, P=0.23), respectively. There was no significant difference between the study groups respecting substance dependence, alcohol and drug abuse, disease history, and the type of exposure (P>0.05). However, self-mutilation, the kind of substance, the vital signs and level of consciousness at admission, and outcomes were significantly different between the research groups (P<0.05). Variables predicting outcomes (complication/death) were as follows: gender (male) (OR: 4.51; 95%CI: 1.51-13.42; P=0.007), the kind of substance (pesticides) (OR: 8.84; 95%CI: 1.78-44.07; P=0.008), time to admission (OR: 1.04; 95%CI: 1.02-1.08; P=0.002), hypotension (OR: 14.88; 95%CI: 3.01-71.58; P=0.001), and the place of hospitalization (ward) (OR: 2.85; 95%CI: 1.23-6.62; P=0.01). Conclusion: The self-mutilation, kind of substance, vital signs, level of consciousness at admission, and outcomes were significantly different between the study patients hospitalized in the ICU, compared to the ward. Gender (male), the kind of substance (pesticides), delayed arrival times, hypotension, and the place of hospitalization (ward) were essential factors for outcome (complication/death) prediction.

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A Ten-Year Study of Drug Poisoning Cases Admitted to the Intensive Care Unit of 5 Azar Hospital in Gorgan, Iran

Cited by 3 publications

References 9 publications

The trend of top five types of poisonings in hospitalized patients based on ICD‐10 in the northeast of Iran during 2012–2018: A cross‐sectional study

The trend of top five types of poisonings in hospitalized patients based on ICD‐10 in the northeast of Iran during 2012–2018: A cross‐sectional study

Development of a risk prediction nomogram for disposition of acute toxic exposure patients to intensive care unit

Clinico-epidemiological Analysis of Adult Patients With Acute Poisoning

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