Sulforaphane (SFN) is an isothiocyanate occurring in broccoli, with exceptional health-beneficial properties, such as anticancer, anti-inflammatory, and antihypertensive effects. Processes to maximize SFN content in broccoli developed until now are expensive and SFN bioavailability in the vegetable is not optimal. To increase SFN extraction yield from broccoli florets, it was proposed to complement traditional solvent extraction with pulsed electric field (PEF) as tissue disruption method enabling the reduction of mass transfer resistance in vegetable matrices. Tissue disruption methods enhance the performance of this process because it reduces mass transfer resistance. PEF is an innovative technology recently introduced in the food industry. We studied the effect of electric field strength (10 and 15 kV/cm) and time of exposure to the PEF treatment (30, 90, and 150 s) on the recovery of SFN from broccoli florets, using a statistical factorial design. Electric field strength and