a-tDCS Differential Modulation of Corticospinal Excitability: The Effects of Electrode Size

Bastani, Andisheh; Jaberzadeh, Shapour

doi:10.1016/j.brs.2013.04.005

Cited by 89 publications

(65 citation statements)

References 38 publications

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“…Overall, the electrode size findings are inconsistent with previous tDCS motor cortex studies, which have reported that smaller electrodes produce either similar or potentially greater changes in cortical excitability compared to larger electrodes [19,20]. However, the stimulus parameters examined in the present study are not identical to those used in previous studies and therefore are not directly comparable.…”

Section: Discussioncontrasting

confidence: 72%

“…Despite the dependence of current density on both current intensity and electrode size, previous studies have examined current intensity and electrode size independent of each other and it has not been possible to separate the effect of current density from current intensity [3,4,[17][18][19][20]. Therefore, the present study examined the two parameters concurrently by analysing the effect of both within a single analysis.…”

Section: A N U S C R I P Tmentioning

confidence: 85%

“…Experimental evidence suggests that smaller target electrodes produce a similar, if not greater, magnitude of effect (i.e., greater change in MEP amplitudes) than larger target electrodes even when current density is held constant [19,20]. Interestingly, computational modelling suggests that the resulting current density on the surface of the brain and within the brain at a fixed depth under the electrodes is lower for smaller electrodes than larger electrodes with the same current intensity-to-electrode size ratio [21][22][23].…”

Section: A N U S C R I P Tmentioning

confidence: 96%

See 2 more Smart Citations

The Effect of Transcranial Direct Current Stimulation (tDCS) Electrode Size and Current Intensity on Motor Cortical Excitability: Evidence From Single and Repeated Sessions

et al. 2016

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Section: Discussioncontrasting

confidence: 72%

Section: A N U S C R I P Tmentioning

confidence: 85%

Section: A N U S C R I P Tmentioning

confidence: 96%

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The Effect of Transcranial Direct Current Stimulation (tDCS) Electrode Size and Current Intensity on Motor Cortical Excitability: Evidence From Single and Repeated Sessions

et al. 2016

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“…In this study, the cathode was of the same size as the anode and cannot therefore be considered merely an inactive reference electrode due to the resulting current density [28]. On the other hand, the unspecificity of the current flow [29] may have allowed modulation of certain prefrontal areas, such as the medial prefrontal cortex (mPFC) and the right DLPFC.…”

Section: Discussionmentioning

confidence: 97%

Effect of transcranial direct current stimulation on semantic discrimination eyeblink conditioning

Kotilainen

Lehto

Wikgren

2015

Behavioural Brain Research

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“…This is consistent with the findings of Hummel et al (2005) that JTT improvements persisted for at least 25 minutes after anodal tDCS. Changes in cortical excitability and intracortical inhibition have also been shown to persist after the stimulation is turned off (Ardolino et al , 2005, Stagg et al , 2009, Di Lazzaro et al , 2012, Bastani et al , 2013b, a, Kidgell et al , 2013, Kim et al , 2014, Moliadze et al , 2014.…”

Section: Discussionmentioning

confidence: 99%

P244 The effect of transcranial direct current stimulation on motor sequence learning and upper limb function after stroke

Fleming

Rothwell

Sztriha

et al. 2017

Clinical Neurophysiology

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. (2017). P244 The effect of transcranial direct current stimulation on motor sequence learning and upper limb function after stroke. CLINICAL NEUROPHYSIOLOGY, 128(3), e133. DOI: 10.1016DOI: 10. /j.clinph.2016 Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. And where the final published version is provided on the Research Portal, if citing you are again advised to check the publisher's website for any subsequent corrections. General rightsCopyright and moral rights for the publications made accessible in the Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognize and abide by the legal requirements associated with these rights.•Users may download and print one copy of any publication from the Research Portal for the purpose of private study or research.•You may not further distribute the material or use it for any profit-making activity or commercial gain •You may freely distribute the URL identifying the publication in the Research Portal Take down policyIf you believe that this document breaches copyright please contact librarypure@kcl.ac.uk providing details, and we will remove access to the work immediately and investigate your claim. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.  Improvement in the Jebsen Taylor Test was seen after unilateral motor cortex tDCS but not after bihemispheric motor cortex tDCS. Changes in performance with tDCS were independent of changes in transcallosal inhibition. AbstractObjective: To assess the impact of electrode arrangement on the efficacy of tDCS in stroke survivors and determine whether changes in transcallosal inhibition (TCI) underlie improvements.Methods: 24 stroke survivors (3-124 months post-stroke) with upper limb impairment participated. They received blinded tDCS during a motor sequence learning task, requiring the paretic arm to direct a cursor to illuminating targets on a monitor. Four tDCS conditions were studied (crossover); anodal to ipsilesional M1, cathodal to contralesional M1, bihemispheric, sham. The Jebsen Taylor hand function test (JTT) was assessed pre-and poststimulation and TCI assessed as the ipsilateral silent period (iSP) duration using transcranial magnetic stimulation. Results:The time to react to target illumination reduced with learning of the movement se...

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a-tDCS Differential Modulation of Corticospinal Excitability: The Effects of Electrode Size

Cited by 89 publications

References 38 publications

The Effect of Transcranial Direct Current Stimulation (tDCS) Electrode Size and Current Intensity on Motor Cortical Excitability: Evidence From Single and Repeated Sessions

The Effect of Transcranial Direct Current Stimulation (tDCS) Electrode Size and Current Intensity on Motor Cortical Excitability: Evidence From Single and Repeated Sessions

Effect of transcranial direct current stimulation on semantic discrimination eyeblink conditioning

P244 The effect of transcranial direct current stimulation on motor sequence learning and upper limb function after stroke

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