Abstract:We present a systematic review on the effect of early intervention, starting between birth and a corrected age of 18 months, on motor development in infants at high risk for, or with, developmental motor disorders. Thirty‐four studies fulfilled the selection criteria. Seventeen studies were performed within the neonatal intensive care unit (NICU) environment. Eight studies had a high methodological quality. They evaluated various forms of intervention. Results indicated that the Newborn Individualized Developm… Show more
“…To our knowledge, this is the first reported meta-analysis of early developmental interventions postdischarge from hospital for preterm infants. A recent review 35 explored the effects on motor outcomes of a range of early interventions that commenced from birth to 18 months in infants at risk for, or with, developmental motor disorders. In the Neonatal Individualised Developmental Care Program, interventions that focus on specific motor training were found to have a positive effect on motor outcomes in high-risk infants.…”
Aim The aim of this study was to review the effects of early developmental intervention after discharge from hospital on motor and cognitive development in preterm infants.
Method Randomized controlled trials (RCTs) or quasi‐RCTs of early developmental intervention programmes for preterm infants in which motor or cognitive outcomes were reported and in which the intervention commenced before or after discharge were included. A systematic review and meta‐analysis of studies grouped by intervention, age of outcome, and study quality was undertaken. Databases searched (up to January 2009) included the Cochrane Central Register of Controlled Trials, MEDLINE, CINAHL, PsycINFO, and Embase.
Results Eighteen studies met the inclusion criteria (2686 patients randomized), but only 11 studies had data suitable for meta‐analysis. Early developmental intervention improved cognitive outcomes at infant age (developmental quotient: standardized mean difference [SMD] 0.42, 95% confidence interval [CI] 0.33–0.52; p<0.001), and at preschool age (IQ: SMD 0.46, 95% CI 0.33–0.59; p<0.001). However, the benefit was not sustained at school age (IQ: SMD 0.02, 95% CI –0.10 to 0.14; p=0.71). Early intervention had little effect on motor outcome at infant or school age, and there was no study reporting motor outcome at preschool age.
Interpretation Current evidence suggests that the benefits of developmental intervention postdischarge are restricted to short‐term gains in cognitive outcome.
“…To our knowledge, this is the first reported meta-analysis of early developmental interventions postdischarge from hospital for preterm infants. A recent review 35 explored the effects on motor outcomes of a range of early interventions that commenced from birth to 18 months in infants at risk for, or with, developmental motor disorders. In the Neonatal Individualised Developmental Care Program, interventions that focus on specific motor training were found to have a positive effect on motor outcomes in high-risk infants.…”
Aim The aim of this study was to review the effects of early developmental intervention after discharge from hospital on motor and cognitive development in preterm infants.
Method Randomized controlled trials (RCTs) or quasi‐RCTs of early developmental intervention programmes for preterm infants in which motor or cognitive outcomes were reported and in which the intervention commenced before or after discharge were included. A systematic review and meta‐analysis of studies grouped by intervention, age of outcome, and study quality was undertaken. Databases searched (up to January 2009) included the Cochrane Central Register of Controlled Trials, MEDLINE, CINAHL, PsycINFO, and Embase.
Results Eighteen studies met the inclusion criteria (2686 patients randomized), but only 11 studies had data suitable for meta‐analysis. Early developmental intervention improved cognitive outcomes at infant age (developmental quotient: standardized mean difference [SMD] 0.42, 95% confidence interval [CI] 0.33–0.52; p<0.001), and at preschool age (IQ: SMD 0.46, 95% CI 0.33–0.59; p<0.001). However, the benefit was not sustained at school age (IQ: SMD 0.02, 95% CI –0.10 to 0.14; p=0.71). Early intervention had little effect on motor outcome at infant or school age, and there was no study reporting motor outcome at preschool age.
Interpretation Current evidence suggests that the benefits of developmental intervention postdischarge are restricted to short‐term gains in cognitive outcome.
“…Early intervention has been shown to improve both cognitive and motor outcomes based on the activation of the plasticity of the brain, which is known to vary with age, and therefore early recognition and referral is essential. 57,58 Communication is key between the neonatal, follow-up clinic, and neurology staff to ensure that proper referrals are made at the time of discharge or at the time neurologic abnormalities are detected or confirmed after discharge to take best advantage of the plasticity window.…”
Neurocritical care is a multidisciplinary subspecialty that combines expertise in critical care medicine, neurology, and neurosurgery, and has led to improved outcomes in adults who have critical illnesses. Advances in resuscitation and critical care have led to high rates of survival among neonates with life-threatening conditions such as perinatal asphyxia, extreme prematurity, and congenital malformations. The sequelae of neurologic conditions arising in the neonatal period include lifelong disabilities such as cerebral palsy and epilepsy, as well as intellectual and behavioral disabilities. Centers of excellence have adapted the principles of neurocritical care to reflect the needs of the developing newborn brain, including early involvement of a neurologist for recognition and treatment of neurologic conditions, attention to physiology to help prevent secondary brain injury, a protocol-driven approach for common conditions like seizures and hypoxic-ischemic encephalopathy, and education of specialized teams that use brain monitoring and imaging to evaluate the effect of critical illness on brain function and development. Semin Pediatr Neurol 21:241-247 C 2014 Published by Elsevier Inc.
“…Konkrete Beispiele hierf ü r sind die multimodalen Konzepte bei der Behandlung der Zerebralparesen oder der Adipositas, niederschwellige Betreuungs-und F ö rderma ß nahmen bei biologischen und psychosozialen Risikofamilien, z. B. den extrem Fr ü hgeborenen und neue Konzepte in der Diagnostik und Therapie von Sprachentwicklungsst ö rungen, umschriebenen Entwicklungsst ö rungen schulischer F ä higkeiten, Intelligenzminderung, ADHS u. a.m. [1,3,4,8,11] . Von besonderer Bedeutung f ü r die sozialp ä diatrische Forschung war die Ver ö ff entlichung des Kinder-und-Jugendlichen-Gesundheits-Surveys durch das Robert-Koch-Institut, an dem mehrere Sozialp ä diater, u. a. U. Thyen, R. und C. Bergmann lungsauff ä lligkeiten, zur Langzeitprognose von sehr und extrem Fr ü hgeborenen, zur Impfteilnahme, zur Erfassung von Kindesvernachl ä ssigungen und Verhaltensst ö rungen sowie zur transkulturellen P ä diatrie [10] .…”
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