A systematic review of silver‐releasing dressings in the management of infected chronic wounds

Lo, Sherman; Hayter, Mark; Chang, Ching‐Jui; Hu, Wen‐Yu; Lee, Ling-Ling

doi:10.1111/j.1365-2702.2007.02264.x

Cited by 87 publications

(52 citation statements)

References 22 publications

(46 reference statements)

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“…There is conflicting evidence about the therapeutic benefits of silver dressings in wound healing: while several systematic reviews have identified positive effects, [24][25][26][27] others have failed to establish any association. 12,28,29 Many studies analysed in these reviews included endpoints relating to healing.…”

Section: Introductionmentioning

confidence: 99%

Silver-containing foam dressings with Safetac: a review of the scientific and clinical data

Davies

McCarty

Hamberg³

2017

J Wound Care

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Phil Davies has more than 25 years of experience of working in healthcare-related industries. During that time, he has authored and contributed to numerous peer-reviewed journal articles and conference presentations (oral and poster) relating to wound care and other areas of healthcare. Phil was awarded a BSc (Hons) Medical Cell Biology and Biochemistry by the University of Liverpool (United Kingdom) in 1989.Sara McCarty was awarded her BSc (Hons) in biomedical sciences in 2008 by the University of Chester, UK. Since then, Sara has gained research experience in the field of wound healing. As a medical writer, she has also authored and contributed to a number of peer-reviewed journal articles and conference presentations. In 2014, she was awarded a PhD in the role and control of matrix metalloproteases in cutaneous wound healing.Kristina Hamberg has over 10 years of experience of working with the design and development of wound care products, particularly those with antimicrobial properties. During that time, she has become an expert within the areas of microbiology and test method development, as well as infection prevention. Kristina was awarded her MSc in food science in 1997 from the University of Kalmar, Sweden, and in 2002 she was awarded a PhD for microbiological evaluation of novel technologies for food preservation by Chalmers Technical University, Gothenburg, Sweden.How to cite this document: Davies, P., McCarty, S., Hamberg, K. Silver-containing foam dressings with Safetac: a review of the scientific and clinical data. J Wound Care 2017; 26: 6 (Suppl. 1), S1-S32. Conclusion S24 References S27Downloaded from magonlinelibrary.com by 054

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Section: Introductionmentioning

confidence: 99%

Silver-containing foam dressings with Safetac: a review of the scientific and clinical data

Davies

McCarty

Hamberg³

2017

J Wound Care

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“…With the advent of antibiotics circa World War II, the use of silver for many of these functions declined, only to be revived in the 1960s by Moyer and Fox, as described below [reviewed in 3]. Several studies failed to show benefit in overall wound healing Some studies favor use of silver-releasing foam dressing [55,60,62], whereas others show higher cost [59,61] Current data do not support routine use of silver for this application…”

Section: Historymentioning

confidence: 99%

“…The results of these studies differ widely, and a recurring theme in the relevant meta-analyses is the need for more rigorous trials before any conclusive statements can be made [54][55][56][57][58]. Because of the countless products available for the management of chronic wounds, both with and without silver, an in-depth review of each is beyond the scope of this review but can be found elsewhere [25,36,37].…”

Section: Topical Application For Ulcersmentioning

confidence: 99%

“…Other concerns related to use of silver dressings are a greater frequency and number of visits and longer total duration of wound care, which may increase costs [61]. Additional studies have had differing results [57], but some suggest that silver dressings increase wear time and therefore improve cost-effectiveness [55,62].…”

Section: Topical Application For Ulcersmentioning

confidence: 99%

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Use of Silver in the Prevention and Treatment of Infections: Silver Review

Politano

Campbell

Rosenberger

et al. 2013

Surgical Infections

165

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Background: The use of silver for the treatment of various maladies or to prevent the transmission of infection dates back to at least 4000 b.c.e. Medical applications are documented in the literature throughout the 17th and 18th centuries. The bactericidal activity of silver is well established. Silver nitrate was used topically throughout the 1800s for the treatment of burns, ulcerations, and infected wounds, and although its use declined after World War II and the advent of antibiotics, Fox revitalized its use in the form of silver sulfadiazine in 1968. Method: Review of the pertinent English-language literature. Results: Since Fox's work, the use of topical silver to reduce bacterial burden and promote healing has been investigated in the setting of chronic wounds and ulcers, post-operative incision dressings, blood and urinary catheter designs, endotracheal tubes, orthopedic devices, vascular prostheses, and the sewing ring of prosthetic heart valves. The beneficial effects of silver in reducing or preventing infection have been seen in the topical treatment of burns and chronic wounds and in its use as a coating for many medical devices. However, silver has been unsuccessful in certain applications, such as the Silzone heart valve. In other settings, such as orthopedic hardware coatings, its benefit remains unproved. Conclusion: Silver remains a reasonable addition to the armamentarium against infection and has relatively few side effects. However, one should weigh the benefits of silver-containing products against the known side effects and the other options available for the intended purpose when selecting the most appropriate therapy.

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“…Chronic wounds, the major healthcare problem, were the wounds that have been stuck in any one of the wound healing phases (hemostasis, inflammation, proliferation, and remodeling) for a period of 6 weeks or more [1,2], and usually exhibit phenomena such as existence of necrotic tissues, lack of healthy granulation tissues, incomplete remodeling of extracellular matrix, incapability of epithelialization, and an interruption in wound improvement [1,3,4]. Many factors, including personal health condition (e.g., diabetes, cardiovascular defects, hepatic diseases, immunodeficiency, aging, cancers, etc.)…”

Section: Introductionmentioning

confidence: 99%

Treatment of Chronic Wounds With the Silver-Containing Activated Carbon Fiber Dressing: Three Cases

2014

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Instead of simply covering and concealing wounds, it is necessary to choose adequate wound dressings to provide proper conditions for wound healing. Silver has long been used clinically throughout the history because of having potent and broad-acting antiseptic properties. Various types of silver-containing wound dressings are commercially available, including activated carbon fiber (ACF)-based silver dressings. ACF possesses two unique and well-known characteristics: a tremendous adsorptive capacity owing to a great network of submicroscopic pores on the surface, and the capability of far-infrared ray emission. Here, we presented three patients with entirely different background. All of them had a chronic wound lasting for several months or years. After they switched the treatment to the silver-containing ACF dressing, their wounds healed in 3 months without any adverse reaction. A randomized controlled trial is merited to test efficacy of this dressing against a recognized standard of care dressing in formerly non-healing wounds.

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A systematic review of silver‐releasing dressings in the management of infected chronic wounds

Abstract: This review strengthens the case for the use of silver dressings when managing infected chronic wounds. They appear more effective and are tolerated well by patients. However, their use should be accompanied by a comprehensive wound assessment.

Cited by 87 publications

References 22 publications

Silver-containing foam dressings with Safetac: a review of the scientific and clinical data

Silver-containing foam dressings with Safetac: a review of the scientific and clinical data

Use of Silver in the Prevention and Treatment of Infections: Silver Review

Treatment of Chronic Wounds With the Silver-Containing Activated Carbon Fiber Dressing: Three Cases

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