A systematic review and meta-analysis of animal-type melanoma

Vyas, Ritva; Keller, Jacob B.; Honda, Kord; Cooper, Kevin D.; Gerstenblith, Meg R.

doi:10.1016/j.jaad.2015.08.016

Cited by 20 publications

(41 citation statements)

References 53 publications

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“…Although almost half of lesions described as PEM were found to have lymph node metastasis in another study, distant metastasis or recurrence after excision is rare . A meta‐analysis of animal‐type melanoma described recurrence in 15 patients out of 190, of which only six had recurrence with distant metastasis . While there is limited evidence pertaining specifically to congenital lesions, overall the data suggest that patients with EBN without Carney complex appear to have a favorable prognosis.…”

Section: Discussionmentioning

confidence: 99%

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Generalized congenital epithelioid blue nevi (pigmented epithelioid melanocytomas) in an infant: Report of case and review of the literature

Blebea

Castelo‐Soccio

et al. 2019

J Cutan Pathol

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The epithelioid blue nevus (EBN) is a variant of the blue nevus characterized by heavily pigmented epithelioid melanocytes and lightly or nonpigmented spindle cells. It may be associated with Carney complex, a multiple neoplasia syndrome. Congenital cases of EBN not associated with Carney complex are rarely reported. We herein describe an infant who presented with multiple blue‐gray nodules and papules involving the head, trunk, and extremities at birth, the corresponding histopathologic findings, and genetic testing results.

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Section: Discussionmentioning

confidence: 99%

“…4,33 A meta-analysis of animal-type melanoma described recurrence in 15 patients out of 190, of which only six had recurrence with distant metastasis. 34 While there is limited evidence pertaining specifically to congenital lesions, overall the data suggest that patients with EBN without Carney complex appear to have a favorable prognosis.…”

Section: Case Reportmentioning

confidence: 99%

Generalized congenital epithelioid blue nevi (pigmented epithelioid melanocytomas) in an infant: Report of case and review of the literature

Blebea

Castelo‐Soccio

et al. 2019

J Cutan Pathol

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“…Pigmented epithelioid melanocytoma appears to occur with equal frequency in men and women, most often in the extremities (38.3%), the head and neck (30.8%), and the trunk (30.8%) [ 29 ]. At diagnosis, the median Breslow depth of the lesions was 3.8 mm, and ulceration was reported in 15.8% of cases.…”

Section: Pigmented Epithelioid Melanocytomamentioning

confidence: 99%

“…At diagnosis, the median Breslow depth of the lesions was 3.8 mm, and ulceration was reported in 15.8% of cases. The presence of a lesion since birth or childhood (34.4% of cases) that expanded in later years has been reported as a distinct clinical feature of this melanoma [ 29 ].…”

Section: Pigmented Epithelioid Melanocytomamentioning

confidence: 99%

Unusual Clinical Presentations of Malignant Melanoma: A Review of Clinical and Histologic Features with Special Emphasis on Dermatoscopic Findings

Cabrera

Reculé

2018

Am J Clin Dermatol

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This review presents the main challenges encountered when diagnosing unusual variants of malignant melanoma with the aim of raising awareness to allow application of the most appropriate treatment strategies. Although these melanomas are often rare, their misdiagnosis potentially jeopardizes patients’ health and survival, and has medicolegal implications. The clinical and histologic presentations of melanoma vary greatly, and assessment of uncommon melanomas can be difficult for practitioners because of their scarcity and resemblance to other dermatologic entities. The most problematic melanoma types are desmoplastic melanoma, polypoid melanoma, primary dermal melanoma, verrucous malignant melanoma, pigmented epithelioid melanocytoma, mucosal melanoma, follicular melanoma and melanoma with non-melanocytic differentiation. The two most difficult-to-diagnose subtypes of melanoma are the nevoid and the amelanotic melanomas. Some specific attributes of these variants can be more easily recognized with digital dermatoscopy, facilitating early detection and possibly avoiding invasive procedures. Key cases with the most notable clinical, dermatoscopic, and histopathologic features are presented, highlighting the practical issues of making an accurate diagnosis and choosing the best therapy.

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“…By systematic review and meta-analysis of the English literature, in 2015, Vyas et al have identified 190 cases of PEM. The median Breslow depth was 3.8 mm, loco-regional recurrence was found in 15 cases, recurrence with distant metastases in 6 cases and death occurred in 5 patients [5]. Recently, Bax et al have suggested that the tumor follows an indolent clinical course, with very low risk of spread beyond regional lymph nodes [6].…”

mentioning

confidence: 99%

Animal-Type Melanoma – a Mini-Review Concerning One of the Rarest Variants of Human Melanoma

Roncati¹,

Piscioli²

2018

Klin Onkol

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A systematic review and meta-analysis of animal-type melanoma

Cited by 20 publications

References 53 publications

Generalized congenital epithelioid blue nevi (pigmented epithelioid melanocytomas) in an infant: Report of case and review of the literature

Generalized congenital epithelioid blue nevi (pigmented epithelioid melanocytomas) in an infant: Report of case and review of the literature

Unusual Clinical Presentations of Malignant Melanoma: A Review of Clinical and Histologic Features with Special Emphasis on Dermatoscopic Findings

Animal-Type Melanoma – a Mini-Review Concerning One of the Rarest Variants of Human Melanoma

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