Animal-Type Melanoma – a Mini-Review Concerning One of the Rarest Variants of Human Melanoma

Roncati, Luca; Piscioli, Francesco

doi:10.14735/amko2018463

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2021

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“…From Levene’s work onwards, the term animal-type melanoma began to spread in dermatopathology to designate this type of lesion, although it already seemed at the time that this nomenclature was too weak and too generic. More in detail, as several papers began to describe this entity in humans [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 ], it became clear that, in humans, it was less malignant than the homologous disease of gray horses [ 10 ], making this nomenclature more and more insufficient to define its salient features.…”

Section: Discussionmentioning

confidence: 99%

“Animal-Type Melanoma/Pigmented Epithelioid Melanocytoma”: History and Features of a Controversial Entity

et al. 2021

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Animal-type melanoma (ATM) was first described in the literature by Levene in 1979 in relation to a patient with a characteristic clinical presentation, and only later, rare and anecdotal case series have tried to shed light on an entity that has undergone several nosographic classification changes, and which, since 2018, is classified under the term “pigmented epithelioid melanocytoma”. Here, we conduct a brief review of the current literature on ATM and present a new clinical case with histopathological, immunophenotypic, and molecular investigations.

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