A systematic review and economic model of the clinical effectiveness and cost-effectiveness of interventions for preventing relapse in people with bipolar disorder

Abstract

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A single blind comparison of lithium and lamotrigine for the treatment of bipolar II depression

“…However, three recent meta-analyses of LTG trials found an overall positive effect, though this wasn't observable on a per study basis Smith et al, 2007;Soares-Weiser et al, 2007). Four double-blind studies assessing LTG for the treatment of BDII have been published to date.…”

Effect of Psychoeducation on Relapses in Bipolar Disorder: A Systematic Review

“…2003 yılında yapılan çalışmanın örneklemini oluşturan 120 hastanın %31'i (37 hasta), DSM-IV kişilik bozukluğu ölçütlerine sahip olduğundan, bu araştırmanın örneklemini oluş-turmuştur. Çalışmada yer alan katılımcıların yaş ortalaması deney grubunda 36 olarak belirlenmiştir. Grupların daha önce yaşadıkları ortalama relaps sayısı deney grubunda 10.18±9.34, kontrol grubunda 9.52±7.19 olarak bulunmuştur.…”

“…Bipolar bozuklukta relaps önleme-ye yönelik yapılan psikoeğitimlerin değerlendirildiği meta analiz çalışmalarından elde edilen bulgular da psikoeğitim gibi tamamlayıcı psikoterapi yöntemlerinin relapsları önlemede etkili olduğunu ortaya koymaktadı. [17,[34][35][36] Bipolar bozuklukta relapsların tekrarlaması, özkıyım riski, relapslar nedeniyle ortaya çıkacak psikososyal sonuçlar ve hastalığa eşlik eden bozukluklar (alkol ve madde kullanım bozuklukları) nedeniyle koruyucu tedavinin gerekliliği tartışılmaz bir durumdur. [37,38] Bu görüşü destekler nitelikte incelenen çalışmaların tamamında uygulanan psikoeğitimin, yaşanan relaps sayılarını azalttığı görülmüştür.…”

Efetividade da Terapia Cognitivo-Comportamental para os Transtornos do Humor e Ansiedade: Uma Revisão de Revisões Sistemáticas

“…Em pacientes com quadro de bipolaridade com predominância depressiva, o melhor tratamento farmacológico verificado -combinado com TCC -tem sido por meio do uso de Valproato, Lítio e Lítio combinado com Imipramina. Em pacientes cuja predominância do transtorno está na fase maníaca, o melhor tratamento tem sido o uso de Olanzapina e TCC (Soares-Weiser et al, 2007).…”