A System of Representation of Cytologic Features of External Eye Infections with Special Reference To Trachoma

Hardy, David C.; Surman, P.G.; Howarth, W.H.

doi:10.1016/0002-9394(67)94143-8

Cited by 6 publications

(1 citation statement)

References 1 publication

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“…According to the system described by Hardy (1966), and Hardy, Surman, and Howarth (1967b), points were allotted for associated cytology considered typical for trachoma infection: 4-6, 3-6, and 2-4 for acute, post-acute, and normal sheep smears, respectively.…”

Section: (E) Associated Cytologymentioning

confidence: 99%

Cytology of ?Pink-Eye" of Sheep Including A Reference to Trachoma of Man, by Employing Acridine Orange and Iodine Stains, and Isolation of Mycoplasma Agents From Infected Sheep Eyes

SURMAN¹

1968

Aust. Jnl. Of Bio. Sci.

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SummaryNumerous forms of a pleomorphic microorganism were observed associated with the cytoplasm of epithelial cells in conjunctival smears from sheep with pink-eye when stained by the Giemsa method. The microorganism was coccobacillary in shape during the acute stage of infection, and stained purplish blue. Various peripheral forms, and dispersed, crescent-, horseshoe-, and ring-shaped figures were present in post-acute smears; all these pleomorphic forms stained blue. Peripheral forms were filaments, blebs, stalked and club-shaped figures, and ring forms. Intracytoplasmic red spherical bodies were the characteristic entity in the epithelial cells of "normal"t sheep smears. The developmental forms of the pink-eye and trachoma agents were morphologically different.Acridine orange staining of representative forms of the pink-eye agent indicated the presence of ribonuleic acid only, in contrast to the demonstration of ribonucleic and deoxyribonucleic acids which appear in sequence during the developmental cycle of the trachoma agent. The iodine method stained the glycogen matrix of trachoma inclusions a brown colour, but a similar stain re/l>Ction was not visible in pink-eye or normal sheep smears.Changes in the cytology of pink-eye smears suggested a gradual replacement of neutrophils successively by large, medium, and small lymphocytes as infection progressed; sometimes plasma cells were present.Mycopla8ma agents were isolated from conjunctival scrapings of sheep with pink-eye. A transmission experiment with one of the isolates produced a mild pinkeye condition. Coccobacillary forms were evident in smears from sheep which developed pink-eye; eye smears from control sheep were normal.It is postulated that the aetiological agents of pink-eye in sheep are Mycoplasma spp. The significance of this finding is discussed in this paper and the syndrome is described.

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Section: (E) Associated Cytologymentioning

confidence: 99%

Cytology of ?Pink-Eye" of Sheep Including A Reference to Trachoma of Man, by Employing Acridine Orange and Iodine Stains, and Isolation of Mycoplasma Agents From Infected Sheep Eyes

SURMAN¹

1968

Aust. Jnl. Of Bio. Sci.

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Cytologic Manifestations of Cervical and Vaginal Infections

Kiviat¹

1985

JAMA

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We used multiple logistic regression to analyze microbiological and clinical correlates of inflammatory and epithelial cell changes on Papanicolaou-stained cervical smears in patients from a sexually transmitted disease clinic. Among randomly selected patients, increased numbers of histiocytes and polymorphonuclear leukocytes and the presence of transformed lymphocytes were associated with Chlamydia trachomatis infection, while increased lymphocytes were associated with Trichomonas vaginalis infection; minimal squamous atypia was associated with yeast infection; and moderate squamous atypia and koilocytosis were associated with cervical condylomata visualized by colposcopy. Among patients referred for cervicitis, C trachomatis infection was also associated with reactive or atypical metaplastic cells. Distinct inclusions were seen by Papanicolaou smear in only 22% of C trachomatis infections. In randomly selected patients, however, the presence of transformed lymphocytes or increased histiocytes had a sensitivity of 95%, a specificity of 75%, and a positive predictive value of 50% in relation to isolation of C trachomatis, and could therefore be used for selection of patients for confirmatory testing for C trachomatis infection.

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The Cytology of Conjunctival Smears from Aboriginal School Children at Yalata, South Australia

Hardy

Surman

Howarth

1967

American Journal of Ophthalmology

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A System of Representation of Cytologic Features of External Eye Infections with Special Reference To Trachoma

Cited by 6 publications

References 1 publication

Cytology of ?Pink-Eye" of Sheep Including A Reference to Trachoma of Man, by Employing Acridine Orange and Iodine Stains, and Isolation of Mycoplasma Agents From Infected Sheep Eyes

Cytology of ?Pink-Eye" of Sheep Including A Reference to Trachoma of Man, by Employing Acridine Orange and Iodine Stains, and Isolation of Mycoplasma Agents From Infected Sheep Eyes

Cytologic Manifestations of Cervical and Vaginal Infections

The Cytology of Conjunctival Smears from Aboriginal School Children at Yalata, South Australia

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