A synergistically enhanced photothermal transition effect from mesoporous silica nanoparticles with gold nanorods wrapped in reduced graphene oxide

Recent Advances in Carbon Nanomaterials for Cancer Phototherapy

“…Later,R GO was utilized by Liu's group as an ew photothermal agent to in vivo treat cancer-thei nv ivo behaviors of various GO derivatives with differents urface coat-ings and sizes were systematically compared by meanso faradiolabeling method. [48] Besides the reduction of GO, GO functionalized by other nanomaterials (e.g.,i ron oxide nanoparticles, [49] Au nanorods, [50] upconversion nanoparticles [51] with NIR absorption) can be also used to enhancephotothermal conversion efficiency.T oi mprovet he therapeutic selectivity,a na ctive targeting strategy has been developed for graphene-based PTT of cancer, in which various active targeted agents, such as Arg-Gly-Asp (RGD), were functionalized onto the surface of graphene. [47,52] In the combination of excellent NIR absorption of graphene and good tumor targetingo fa ctive targeted agents, the resultant nanohybrids have efficient PTT efficacy in vitro and in vivo.…”

Understanding the driving forces of camptothecin interactions on the surface of nanocomposites based on graphene oxide decorated with silica nanoparticles

“…The main nanocarriers include graphene oxide (GO), 22-24 mesoporous silica nanoparticles (MSNs) [25][26][27] and a new family of nanocomposites based on graphene oxide decorated with silica nanoparticles (GO-MSNs). 28,29 Graphene oxide is a two-dimensional carbon nanomaterial comprising regions of carbon atoms with sp 2 hybridization and sp 3 carbons associated with oxygenated functional groups, including carboxylic acid, ketone, aldehyde, epoxide, hydroxyl and lactol groups. 30 This material intrinsically has interesting characteristics, such as good water dispersibility, high mechanical strength and a signicant theoretical surface area (2630 m 2 g À1 ).…”

Mesoporous Manganese Dioxide Coated Gold Nanorods as a Multiresponsive Nanoplatform for Drug Delivery

“…The amount of dissociative DOX was calculated based on the standard curve of the concentration–absorption value. The following equations were used to calculate the DOX content and drug loading efficiency of Au/MnO 2 nanoparticle: , …”

“…The amount of dissociative DOX was calculated based on the standard curve of the concentration−absorption value. The following equations were used to calculate the DOX content and drug loading efficiency of Au/MnO 2 nanoparticle: 40,41 For the in vitro drug release experiments, GSH solution (1.0 mL), phosphate buffer solution (PBS; pH 7.4), and acetate buffer solution (ABS; pH 4.5) were added to the dialysis bag, respectively. After that, the drug-loaded nanoparticles were dispersed in the dialysis bag with different solutions.…”