A Survey of Leukaemia in Cornwall, 1948-1959

Wood, Eileen E.

doi:10.1136/bmj.1.5188.1760

Cited by 19 publications

(3 citation statements)

References 5 publications

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“…In conclusion, the present study represents the first study of leukaemia morbidity with the possible exception of the small study by Wood (1960) in which it has been possible to subclassify virtually all cases into the 4 main types of leukaemia and to characterize each of these types accurately.…”

Section: Discussionmentioning

confidence: 78%

Population‐Based Age‐ and Sex‐Specific Incidence Rates in the 4 Main Types of Leukaemia

Brincker

1982

Scandinavian Journal of Haematology

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Due to recent developments in clinical haematology, 98.8 % of all 1980 cases of leukaemia reported to the Danish Cancer Registry during the 4-year period 1973-76 could be subclassified into the 4 main types of leukaemia. Thus, it has been possible to characterize each of these types more accurately than before regarding age-and sex-specific incidence rates, relative frequency, male/female ratio, and median age at diagnosis. Chronic lymphatic leukaemia constituted 38 '90 and chronic myeloid leukaemia 15 '90 of the cases. These figures are larger and smaller, respectively, than these previously reported. The median age of all cases combined was 67 years, and the median age in cases of acute non-lymphocytic leukaemia was 64 years with 59 % of the latter patients more than 60 years of age. In childhood myeloid leukaemia, an early incidence peak, not previously described, was observed before the age of 2 years. Analysis of Danish leukaemia incidence rates from 1943 and onwards shows no increase over 3 decades in patients less than 75 years of age. Thus, the observed increase in incidence from 5866-9942/100000 during the period studied is limited to the very oldest age groups and is probably due to improved diagnostic efforts.

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Section: Discussionmentioning

confidence: 78%

Population‐Based Age‐ and Sex‐Specific Incidence Rates in the 4 Main Types of Leukaemia

Brincker

1982

Scandinavian Journal of Haematology

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“…A few thousand houses in the UK deliver annual doses ofmore than 50 mSv (Wrixon et al, 1988): a few tens may be delivering doses above 500 mSv (O'Riordan, 1990). It is not generally thought that high levels of radon are associated with leukaemia (Wood, 1960), although at least one study has suggested that there may be such a link (Henshaw et al, 1990).…”

Section: Ionising Radiationmentioning

confidence: 99%

Advances in Nuclear Science and Technology

2002

Advances in Nuclear Science and Technology

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PREFACEAs we close on the Millennium we also approach a half-century of nuclear power. The major peaceful application centres on the large-scale production of electricity but international politics in the last year has shown that we have not left the origins in nuclear weapons behind. Can we assess the future of nuclear technology in the coming century?Electricity remains the dominant role for nuclear technology, though we may recognise the valuable contributions of radio-isotope work to biology, agriculture, disease control, medical diagnostics and therapy in particular, with ramifications in most industries and civilised life. The supply of electricity from nuclear power remains of the order of 10% in the USA but rises to one-third in the UK and on to some 80% in France. Far Eastern countries still have a major construction program that might lead to them rivalling such figures. Indeed if we are to accept the majority judgement of scientists that global warming through, principally, carbon dioxide is a realistic threat, it is to be hoped that nuclear power will indeed be maintained and increased to balance the almost inevitable expansion of the use of coal by China in particular. Claims that countries such as Sweden will reduce CO2 emission and simultaneously reduce nuclear power seem but a chimera, lacking all technical credibility.The down-side remains, however. Not only is the world still threatened with nuclear weapons, by repute or even testing, but no country has had the political will to manage the disposal of radio-active wastes, not just the Achilles heel but the foot, shin and leg of nuclear power. Many scientists and engineers will suppose that this is solely a political problem, claiming that the technical solutions are available. Unfortunately, it makes it no less a problem and renders the prospect of continued, let alone expanded nuclear power, no less vulnerable for being political. And who amongst the technicians is wise to say that the atavistic public perception of the threat of nuclear power is irrational when sabre rattling by emerging weapons powers echoes throughout the world?We see an interesting parallel in the modern development of genetically engineered plants and animals, to be compared with the last halfcentury of nuclear power. In the bright dawn of the post-war nuclear age, the public by-and-large accepted the claims made for the promise of the cheap production of electricity but have largely turned, or been turned by the media, against nuclear power. Do we see the same hubris mounting for those microbiologists who dismiss risks of genetic contamination of agriculture or dismiss the change in insurance attitudes when the threads of DNA predict our future like the threads of the Fates, those Spinners of the Years? Take note of the history of Nuclear Power and prepare for the backlash.If trust is to be restored in the civil use of nuclear power, rational and careful study must be made of its problems, and the results made available publicly, as instanced by the first article in this ...

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“…Statistical data collected in Sweden and Philadelphia, U.S.A., suggest that there is a genetic susceptibility to lymphosarcoma in cattle. "Clustering", or an abnormally high incidence of leukaemia in certain geographical areas in a certain time, has been described for childhood lymphatic leukaemia particularly in Fowey and Newquay in Britain (Wood, 1960).…”

Section: (A) Virusesmentioning

confidence: 99%