A Survey for Intestinal Helminths in Recently Wild-Caught Macaco mulatta and Results of Treatment with Mebendazole and Thiabendazole

Abstract

One hundred Macaco mulatta, trapped in India and transported directly to the California Primate Research Center, were surveyed for the prevalence of gastrointestinal helminths. Trichostrongylus sp. was found in 86% of the animals, followed by Strongyloides fulleborni (63%), Streptopharagus sp. (38%), Oesophagostomum sp. (23%) and Anatrichosoma sp. (21%). Treatment with mebendazole and thiabendazole was efficacious against all the intestinal nematodes, with the exception of mebendazole versus Streptopharagus sp.

Gastro-intestinal helminths in a natural population ofMacaca sinica andPresbytis spp. at Polonnaruwa, Sri Lanka

“…This is consistent with other investigations on Asian macaques (KARR et al, 1980;REMFRY, 1978REMFRY, , 1982. Although the home range of the langurs overlaps that of the toque macaques, only the stools of all the grey langurs were positive for Trichuris.…”

Mebendazole in the treatment of Hymenolepis nana infections in the captive ring-tailed lemur (Lemur catta), China

“…Mebendazole is often used to control gastrointestinal nematodes in nonhuman primates, being highly effective, broadspectrum, and safe (Brack and Rietschel 1986;Dufour et al 2006;Karr et al 1980;Wang et al 2008). In our study, there was no clinical or pathological evidence of toxicosis and no adverse side effects at a dose of 10 mg/kg administered once per day for 5 days.…”

Overview of known non-human primate pathogens with potential to affect colonies used for toxicity testing

“…Common helminths include species of Strongyloides, Oesophagostomum, Anatrichosoma, Trichostrongylus, and Gongylonema, and larval stages of nematodes (ascarids, spirurids), cestodes (hydatid, Sparganum), and pentastomids (Wong and Conrad, 1978;Karr et al, 1980;Sano et al, 1980). Although treatment with anti-helmintics has significantly reduced or eliminated these infestations, Strongyloides fuelleborni has been difficult to eradicate completely, with infection rates as high as 27% reported in domestic colonies of macaques (Eberhard, 1981;Sestak et al, 2003;Dufour et al, 2006).…”