This case study aims to describe the Republic of Korea's preparedness and response to coronavirus disease 2019 (COVID-19) and the resultant impact of the pandemic on the health of its citizens and the economy. Korea has been recording COVID 19-related epidemiological data since January 20, 2020, when the first imported confirmed case of COVID-19 occurred. Since then, Korea has undergone four surge waves, which posed different challenges and cumulative negative impacts. The government implemented and revised social distancing policy measures, as appropriate, to maintain a balance between acceptable risk and disease burden, while promoting vaccination. The fiscal policy also has kept an expansionary stance to cushion the economic effects of the pandemic.