A study on the safety and efficacy of bovine bone-derived bone graft material(OCS-B)

Park, Ho Nam; Han, Sang Hyuk; Kim, Kyoung Hwa; Lee, Sang Chul; Park, Yoon Jeong; Lee, Sang Hoon; Kim, Tae Il; Seol, Yang Jo; Ku, Young; Rhyu, In‐Chul; Han, Soo Boo; Chung, Chong Pyoung

doi:10.5051/jkape.2005.35.2.335

Cited by 2 publications

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“…This new DBBM was produced for the present cases according to previously published methods [ 6 ]. Bone from the bovine femur was cut into 5-cm 3 pieces.…”

Section: Introductionmentioning

confidence: 99%

“…In an in vivo study, DBBM particles were grafted into rat muscle to evaluate biocompatibility. During the 2 weeks of the graft, DBBM particles did not show any inflammatory cell infiltration and were encapsulated by a fibrous tissue [ 6 ]. In a rabbit calvarial defect model, new bone was formed and fused using DBBM particles after 2 weeks.…”

Section: Introductionmentioning

confidence: 99%

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Long-term results of new deproteinized bovine bone material in a maxillary sinus graft procedure

Shin

Hwang

Kim

et al. 2014

J Periodontal Implant Sci

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PurposeThe aim of this case report is to present the longitudinal results of sinus grafting using a new demineralized bovine bone material (DBBM) in human cases.MethodsA patient with a resorbed maxilla was treated by maxillary sinus grafting using a new deproteinized bovine bone material. After a healing period of 6.5 months, three implants were placed and restored. The patient was periodically recalled and followed up for 5 years after restoration.ResultsTwelve partially edentulous patients (average age, 55.7 years) were followed up. All patients had insufficient residual height in their maxillary posterior area and underwent maxillary sinus graft surgery to increase the height of their maxilla. In all, 27 fixtures were placed in the augmented bone area. On average, 8.6 months later, implants were loaded using provisional or final restorations. The observation period ranged from 27 to 75 months (average, 43.3 months), and the patients did not show any severe resorption of the graft material or any infection during this time.ConclusionsOur results show that the new DBBM is useful for a maxillary sinus graft procedure. Good healing responses as well as reliable results were obtained for an average follow-up period of 43.3 months.Graphical Abstract

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“…This new DBBM was produced for the present cases according to previously published methods [ 6 ]. Bone from the bovine femur was cut into 5-cm 3 pieces.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Long-term results of new deproteinized bovine bone material in a maxillary sinus graft procedure

Shin

Hwang

Kim

et al. 2014

J Periodontal Implant Sci

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Comparison of the Volume and Histological Properties of Newly Formed Bone after the Application of Three Types of Bone Substitutes in Critical-Sized Bone Defects

Esfandiari

Amid

Kadkhodazadeh

et al. 2024

J Long Term Eff Med Implants

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This study aimed to compare the volume and quality of the newly formed bone following application of two types of xenografts and one synthetic material in bone defects in rabbit calvaria from histological and micro-CT aspects. Four 8-mm defects were created in 12 rabbit calvaria. Three defects were filled with bone substitutes and one was left unfilled as the control group. The newly formed bone was evaluated histologically and also by micro-CT at 8 and 12 weeks after the intervention. The percentage of osteogenesis was comparable in histomor-phometric assessment and micro-CT. Histological analysis showed that the percentage of the newly formed bone was 10.92 ± 5.17%, 14.70 ± 11.02%, 11.47 ± 7.04%, and 9.45 ± 5.18% in groups bovine 1, bovine 2, synthetic, and negative control, respectively after 8 weeks. These values were 33.70 ± 11.48%, 26.30 ± 18.05%, 22.92 ± 6.30%, and 14.82 ± 8.59%, respectively at 12 weeks. The difference in the percentage of the new bone formation at 8 and 12 weeks was not significant in any group (P > 0.05) except for bovine 1 group (P < 0.05). Micro-CT confirmed new bone formation in all groups but according to the micro-CT results, the difference between the control and other groups was significant in this respect (P < 0.05). All bone substitutes enhanced new bone formation compared with the control group. Micro-CT assessment yielded more accurate and different results compared with histological assessment.

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A study on the safety and efficacy of bovine bone-derived bone graft material(OCS-B)

Cited by 2 publications

References 0 publications

Long-term results of new deproteinized bovine bone material in a maxillary sinus graft procedure

Long-term results of new deproteinized bovine bone material in a maxillary sinus graft procedure

Comparison of the Volume and Histological Properties of Newly Formed Bone after the Application of Three Types of Bone Substitutes in Critical-Sized Bone Defects

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