Because of the rapid development of social economy and urbanization, people's quality of life has been significantly improved, while people's requirements for housing construction. The requirements of space and environment are also increasing. To effectively meet people's needs, it is necessary to dig deeper into the functions of buildings, increase innovation, promote the integration of architecture and structure, and increase the development growth and to contribute a high level of construction building design. This paper discusses the application of structural design innovation in architectural design, discusses architectural structure design principles, and discusses design innovation countermeasures from the level of integration of architecture and structure in order to promote the further development of the construction industry.