A Study on Status of Vitamin D3 Level Among Patients Diagnosed as Case of Hypothyroidism in a Medical College, Tripura

Islam, Tahidul; Choudhury, Sangita; Datta, Asoke G.

doi:10.18410/jebmh/2019/203

Cited by 2 publications

(3 citation statements)

References 18 publications

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“…The present study showed decreased mean vitamin D levels in the study group, which were significantly (p<0.01) lower than those in the control group. This finding has been supported by different researchers from different countries [22,23,27,28,34,37,38]. Furthermore, there were no significant differences in vitamin D between the different age groups in the study group.…”

Section: Vitamin Dsupporting

confidence: 73%

“…Furthermore, serum vitamin D decreased when the TSH level increased and vice versa. Various researchers from different countries have observed a similar correlation between vitamin D and TSH [25,27,37]. These results suggested that there may be a significant association between vitamin D deficiency and hypothyroidism.…”

Section: Correlation Between the Tsh Vitamin D And Ironmentioning

confidence: 53%

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Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study

Shimmi¹,

Eldosouky²,

Parash³

et al. 2023

Cureus

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Background: Hypothyroidism is the most common pathophysiological condition that affects mostly females in both developed and developing countries. Data on hypothyroidism among adult females are essential to understand the underactive status of the thyroid gland among the female population and its correlated effects on a deficiency of vitamin D and iron, as effective prevention of osteoporotic changes and iron deficiency anemia is possible. Therefore, the present study was designed to investigate the probability of concurrent iron and vitamin D deficiency among the adult hypothyroid female population of Abu Dhabi, UAE.Materials and methods: This cross-sectional study was carried out from September 2019 to July 2021 among 500 adult females aged 18 to 45 years old in Sheikh Shakhbout Medical City (SSMC) and Sheikh Khalifa Medical City (SKMC), Abu Dhabi, UAE. After obtaining written informed consent, subjects' demographic characteristics (sun exposure, dressing code, food consumption), anthropometry (height, weight, BMI), and biochemical parameters (thyroid profile, vitamin D profile, iron profile, and blood indices) were measured.Results: In this study, serum vitamin D and iron levels were significantly (p<0.01) decreased in the hypothyroid female group (study group). The serum vitamin D and iron levels showed a significant negative (p<0.01) correlation with thyroid-stimulating hormone (TSH). Out of 250 study group participants, 61 had a concurrent deficiency of serum vitamin D and iron, yielding a probability (P of low vitamin D and iron and hypothyroidism) of 0.244, which indicates that if 1000 hypothyroid patients are tested for serum vitamin D and iron levels, 24 patients are probable to have low vitamin D and iron. Conclusion:The study concluded that vitamin D and iron bi-deficiency were observed in adult hypothyroid females in Abu Dhabi, UAE. So, the routine check-up of thyroid function and vitamin D and iron profiles should be done early. Therefore, early vitamin D and iron deficiencies can be detected, and supplements can be given to prevent further health complications like osteoporosis and iron deficiency anemia.

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Section: Vitamin Dsupporting

confidence: 73%

Section: Correlation Between the Tsh Vitamin D And Ironmentioning

confidence: 53%

Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study

Shimmi¹,

Eldosouky²,

Parash³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…Islam et al 38 measured vitamin D and TSH for 45 females (hypothyroid individuals aged 25-65 years). Vitamin D decreased significantly in hypothyroid individuals (19.2 ± 1.40 ng/mL) compared to the control group (28.4 ± 1.36 ng/mL, P < 0.001).…”

Section: Studies About the Relation Of Hypothyroidism With Vitamin Dmentioning

confidence: 99%

Hypothyroidism and its effect on serum vitamin D and iron among adult female: A review from Middle East perspective

et al. 2022

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Hypothyroidism is a pathophysiological phase in which insufficient hormones are produced leading to an imbalance in basal metabolic rate and inefficiency physiological role of body systems. Vitamin D affects thyrocytes by decreasing TSH stimulated iodide uptake and cellular development. In hypothyroidism, hypovitaminosis D are due to malabsorption from the intestine and the other mechanism is inactivation of vitamin D. Thyroid hormones induce erythropoietin gene expression causing increase secretion of erythropoietin. Iron deficiency decreases activity of thyroid peroxidase enzyme. Hypothyroidism can cause microcytic anemia due to malabsorption of iron and menorrhagia. Hypothyroidism is a common but under-recognized and under-diagnosed condition in the Persian Gulf countries. Moreover, the effect of hypothyroidism on vitamin D and iron levels were inadequately evaluated. This is important to identify bi-deficiency so that, doctors can treat them earlier and can reduce the deficiency-related complications. There are plenty scopes for study on bi-deficiencies status of hypothyroid population.

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A Study on Status of Vitamin D3 Level Among Patients Diagnosed as Case of Hypothyroidism in a Medical College, Tripura

Abstract: BACKGROUND Vitamin D3 receptors are present in different body tissues like myocardium, pancreas, thyroid gland etc. Since both Vitamin D3 and thyroid hormones act via steroid receptors, any alteration in the level of Vitamin D3 is likely to increase problems associated with hypothyroidism.

Cited by 2 publications

References 18 publications

Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study

Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study

Hypothyroidism and its effect on serum vitamin D and iron among adult female: A review from Middle East perspective

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