A study on incidence of congenital anomalies in newborns and their association with maternal factors: a prospective study

Thaddanee, Rekha; Patel, Hemant S.; Thakor, Nilesh

doi:10.18203/2349-3291.ijcp20161042

Cited by 5 publications

(5 citation statements)

References 3 publications

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“…It was caused by the correlation between advanced maternal age with chromosomal abnormality in fetus. A three-years prospective study from India showed that maternal age has statistically significant association with congenital fetal anomalies (Thaddanee et al, 2016). However, this was contrary with our study.…”

Section: Resultscontrasting

confidence: 99%

Clinical Characteristic of Congenital Fetal Anomaly In Tertiary Referral Hospital in East Java, Indonesia

Amani

et al. 2021

IIMJ

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Background: Congenital fetal anomalies were defined as any structural defect present at birth. Congenital fetal anomalies are an important causes of neonatal morbidity and mortality in developed and developing countries that affect health care system. Reliable data on these congenital anomalies are still lacking, especially in Indonesia. Objective: This study aims to determine the characteristic profile of congenital fetal anomaly in single tertiary hospital in East Java, Indonesia. Methods: Retrospective cross-sectional by using medical record data of dr. Soetomo General Hospital on January – December 2017. Results: There were 58 cases (4,3%) with fetal congenital anomaly from 1360 deliveries in 2017. The majority of cases were referral cases (51 cases; 88%) and only seven cases were booked cases in obstetric outpatient dr. Soetomo General Hospital. Most of these congenital fetal anomaly cases ( 25 cases / 43,1%) were born from mother with ages 20 – 30 years old. Most cases (34 cases; 58,64%) were diagnosed first at third trimester (gestational age > 28 weeks). There were 36 cases (62%) had active termination of pregnancy. Thirty eight percent (22 cases) were born at 37-42 weeks and majority were born section caesaria. The three highest proportion of organ systems involved in fetal congenital anomalies were those of abdomen (22 cases; 37,9%); head (20 cases; 34,5%); thorax and muskuloskeletal (each 12 cases; 20,7%). Conclusion: The incidence of congenital fetal anomaly in dr. Soetomo Hospital at 2017 was 4,3%. Omphalocele and CTEV were two most common types of congenital fetal anomaly found. Most cases of congenital fetal anomalies have a poor prognosis, 67% cases born died. Further research about risk factors and comprehensive database are needed on cases of congenital anomaly to establish appropriate prevention and management.

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Section: Resultscontrasting

confidence: 99%

Clinical Characteristic of Congenital Fetal Anomaly In Tertiary Referral Hospital in East Java, Indonesia

Amani

et al. 2021

IIMJ

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“…A similar result was found in a study done by Thaddanee R et al in 2016. 13 The Association of antenatal check-up with congenital anomalies is statistically not significant in our study.…”

Section: Discussioncontrasting

confidence: 62%

“…On the contrary, the association was significant in the study done by Thaddanee R et al in 2016. 13 In our study it is found that the association of maternal education with congenital anomalies is statistically significant (P value-0.00001). Similar result was found in a study done by Dingemann C et al in 2019.…”

Section: Discussionsupporting

confidence: 48%

Study of Congenital Malformation in a Tertiary Care Teaching Hospital

Sahoo

Ganguly²,

Dash³

et al. 2021

Siriraj Med J

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Objective: Congenital anomaly is one of the most important causes & being the 5th most common cause of neonatal mortality & morbidity. It may present as a structural or functional abnormality. These defects occur due to defective embryogenesis. Associated factors may be maternal age, maternal TORCH infection, drugs, genetic factors. Antenatal USG reduces the incidence.Materials and Methods: A cross-sectional study was done in the Pediatric department over 1 year. Diagnosis of all congenital anomalies was done by the concerned pediatrician& pediatric surgeon. Data was collected in the specified format.Results: A total of 10205 cases of age group 1 month to 5 years presented to the paediatric OPD, out of which 193 children were diagnosed as congenital anomalies in 1 year. Males were found to be affected the most. The most common system involved was found to be the genitourinary system (36.78%). The second most common system involved was the gastrointestinal system (33.67%). The least common system involved was the musculoskeletal system.Conclusion: Congenital anomalies are a major cause of neonatal & infantile mortality & morbidity. Routine screening with a level II targeted scan for all the pregnant mothers should be mandatory. Adequate nutrition, parental education & Rubella vaccination of the mother can decrease the prevalence of congenital anomalies to some extend.

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“…Most common mode of delivery was LSCS in this study which was similar to Sarkar et al study. There was no much difference in congenital anomalies based on gender in our study but Sarkar et al, [11] Ara et al and Shah et al found that male gender is more commonly affected than female.…”

Section: Discussioncontrasting

confidence: 61%

A Study on Spectrum of Congenitalanomalies Delivered in a Tertiary Care Center

Kantamneni¹,

Prasad²,

Deepthi³

2020

ijsr

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INTRODUCTION: Congenital anomaliesaccount for 9% of neonatal deaths in India. Prevalence of birth anomalies in India is 6-7%. AIMS AND OBJECTIVES: The objective was to determine proportion and clinical spectrum of congenital anomalies and maternal and perinatal risk factors associated with congenital anomalies in live newborns in our area. MATERIALS AND METHODS: Neonates born in ALLURI SITARAMA RAJU ACADEMY OF MEDICAL SCIENCES hospital during study period with documented congenital anomalies are included. All still-borns and gestational age <22wks & birth weight <400gm were excluded. Retrospective hospital-based study, conducted between January 2019 to December 2019 in ASRAM Hospital. RESULTS: The total number of births is 1132 during this one year of which, 106 newborns had congenital anomalies. In this study we found that major anomalies (80.2%) , Minor anomalies (19.8%).In this study we found that most of the anomalies were major and mostly involved cardiovascular system. In minor anomalies the most common defect was sacral dimple. CONCLUSION: Congenital anomalies can be reduced with in-utero surgeries, and necessary preventive measures which are becoming feasible.

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A study on incidence of congenital anomalies in newborns and their association with maternal factors: a prospective study

Cited by 5 publications

References 3 publications

Clinical Characteristic of Congenital Fetal Anomaly In Tertiary Referral Hospital in East Java, Indonesia

Clinical Characteristic of Congenital Fetal Anomaly In Tertiary Referral Hospital in East Java, Indonesia

Study of Congenital Malformation in a Tertiary Care Teaching Hospital

A Study on Spectrum of Congenitalanomalies Delivered in a Tertiary Care Center

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