A study on blood eosinophil level and ventilatory pulmonary function of the workers exposed to storage grain dust

Abstract

The workers engaged in storage grain handling are exposed to storage grain dust and suffer from different respiratory symptoms like, cough wheezing, chest tightness, eye and nasal irritations. It has been reported abroad and the present study results noted that the grain handlers have allergic symptoms like redness of eyes, itching, sneezing, skin rash, breathlessness and decrement of pulmonary function test values. According to their nature of job, the workers of storage grain godowns were divided into four categories i.e., load handling worker (LHW), ancillary, quality control and depot administration workers. The pulmonary function tests (PFT) and the differential count of leucocytes were carried out among the workers by standard technique. Decrement of pulmonary function test values was noted with the increment of blood eosinophil level.The PFT results were presented according to the blood eosinophil level. The decrement of mean PFT values were noticed as the blood level of eosinophil gradually increased from, up to -4%, >4-10% and above 10%. The maximum numbers of workers in different job categories are belonged to >4 -10% of eosinophil level. The percentage figure of workers in different departments were LHW 48.38%, (n=45), ancillary 38.88%, (n=7), quality control 54.54% (n=6) and depot administration workers 47.05% (n=16) are belonged to that range. Among the total workers the higher figure was found >4-10% ranges 47.43% (n=74) workers. The allergic manifestations like redness, itchiness and watering of eyes, sneezing, cough, breathless etc. are reported. These workers have blood eosinophil level and low pulmonary function test values. The respiratory impairments among the workers are restrictive, obstructive and combined restrictive and obstructive type.

Haematological Parameters, Serum Biochemistry and Gut Microbial Count of Broiler Chicks Fed Processed Dietary Fungi Treated Jatropha curcas Kernel Meals

“…The range obtained in this study showed that the birds were not anaemic. The high level of eosinophyll in birds fed LDFM and ZDFM could be attributted to destructive type of pulmonary dysfunction as reported by Chattopadhyay et al [22]. Eosinophyll had been reported to play a primary role in detoxification.…”

Deterioration of lung function and its association with eosinophil count

“…Interleukin (IL)-4, IL-5 and IL-13, plays a vital role in the pathophysiology of eosinophilic airway diseases such as asthma, chronic rhinosinusitis, eosinophilic granulomatosis with polyangiitis and hypereosinophilic syndrome [ 22 ]. Studies have reported the association of blood eosinophils with lower FEV1 in asthmatic patient and a significant decline in FEV1 in COPD patients [ 5 ]. However, there is apaucity on how the eosinophils increases with an increased decline in the lung function.…”

“…Eosinophilia in the peripheral blood is typically considered a sign of allergies. Numerous studies have shown a connection between peripheral blood eosinophil levels and pulmonary function impairment [ 5 ]. Quarry employees experience a variety of allergy reactions brought on by dust, which can result in eosinophilia.…”

Peak Expiratory Flow Rate and Eosinophil Count in Jute Workers: A Cross- Sectional Study

“…Sordrager et al (1995) [20] [21] narrated that the PEFR results were presented according to the blood Eosinophil level. The decrement of mean PEFR level were noticed as the blood levels of eosinophils were gradually increased from 4-10% the maximum number of workers belong to higher Eosinophil levels which is similar to our study.…”