A Study on Adverse Drug Reactions in a Tertiary Care Hospital of South India

Abstract

Medication-related adverse events or adverse drug reactions (ADRs) are harmful events caused by medication. ADRs could have profound effects on the patients’ quality of life, as well as creating an increased burden on the healthcare system. ADRs are one of the rising causes of morbidity and mortality internationally, and will continue to be a significant public health issue with the increased complexity in medication, to treat various diseases in an aging society. This was a prospective and observational study conducted in medicine department of sagar hospital, Bengaluru. Patients were enrolled based on the criteria with a suitable statistical tool. Among 64 patients, 33 (51.6%) female and 33 (48.44%) were males found. ADRs were more in the age group of 41 – 60, 32 (50%), less in the age group is 0 – 20, 04 (6.25%). Significantly higher numbers of ADRs caused by the antibiotics 25 (39%) followed by antihyperlipidicmic and anti-arrythmic 01 (1.56%), Most of the ADRs were moderate 40 (62.5%) and sever 01 (1.56%) in nature. Most commonly affected organ is dermatological system 32 (50%). Majority of the ADRs were associated with antibiotics. Commonly skin related ADRs was found in this study. The results provided an insight to the Health care Providers on the importance of monitoring and reporting of ADRs. Our study results emphasize a need for establishing a pharmacovigilance centre to ensure the safe use of drugs.