This paper presents the optimization of 2-phase interleaved DC-DC boost converter (IBC) in order to achieve switching device losses and current stress reduction. Principally, the distributed of input currents in 2phase IBC can reduce the current stress on components i.e., inductor and switching devices, consequently the lower rating of inductor and switching device can be considered. However, the interleaving technique does not reduces the inductor current ripple in 2-phase IBC. The comparison of switching device losses and the current stress for conventional DC-DC boost converter (1-phase IBC), 2-phase IBC, and 3-phase IBCs are provided in this paper. The 180-degree phase-shifted pulse width modulation technique (PWM) is implemented on the 2-phase IBC. The results show that by increasing the phase number of IBCs, 1-phase, 2-phase and 3-phase, the switching device losses are reduced i.e., 76 mW, 30 mW, and 22 mW, respectively. Meanwhile, the inductor current stresses is reduced as well, i.e., 0.8 A, 0.4 A, and 0.27 A, respectively. The finding shows the conduction loss decreases when the phase number of IBC increases. However, this will increases the switching loss of the IBC. Thus, the 2phase IBC is selected as the optimum phase of IBC with regards to the switching loss and conduction loss consideration of the semiconductor devices.