2000
DOI: 10.1002/(sici)1099-1573(200005)14:3<203::aid-ptr565>3.0.co;2-r
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A study of the trypanocidal and analgesic properties from Lychnophora granmongolense (Duarte) Semir & Leit�o Filho
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Cited by 60 publications
(42 citation statements)
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“…Goyazensolide is a natural sesquiterpene lactone found in plants of the Asteraceae family [11,41,44–48] . While it boasts a variety of biological activities including schistosomicidal, [11] trypadocinal, [4,46,49] antimycobacterial, [47] cytotoxic, [47,48,50] genotoxic [51] and anti‐hyperuricemic, [52] the exact mode of action behind goyazensolide and its related furanoheliangolides remained elusive.…”
Section: Resultsmentioning
confidence: 99%
“…Goyazensolide is a natural sesquiterpene lactone found in plants of the Asteraceae family [11,41,44–48] . While it boasts a variety of biological activities including schistosomicidal, [11] trypadocinal, [4,46,49] antimycobacterial, [47] cytotoxic, [47,48,50] genotoxic [51] and anti‐hyperuricemic, [52] the exact mode of action behind goyazensolide and its related furanoheliangolides remained elusive.…”
Section: Resultsmentioning
confidence: 99%
“…Taxifolin ( 24) is a well-known natural compound, and blumeatin A (23) was described in Blumea balsamiferia. 30 The vanilloid isomer 22 occurs as trace component (5 mg/kg) besides HED (1) in Lychnophora granmongolense ("Brazil arnica"), 31 whereas the isomer 25, which is related to the flavanone sterubin, was also found in Blumea balsamiferia. 32 Dihydromyricetine or ampelopsin (26) was found in Ampelopsis cantoniensis.…”
Section: ■ Results and Discussionmentioning
confidence: 99%
“…The NOEDIFF experiments confirmed all relative stereochemistry for each structure and some previously ambiguous carbon assignments were also clarified. C NMR data for centratherin (2). 500MHz, CDCl 3 …”
Section: Resultsmentioning
confidence: 99%
