2000
DOI: 10.1002/(sici)1099-1573(200005)14:3<203::aid-ptr565>3.0.co;2-r
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A study of the trypanocidal and analgesic properties from Lychnophora granmongolense (Duarte) Semir & Leit�o Filho

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Cited by 60 publications

(42 citation statements)
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“…Goyazensolide is a natural sesquiterpene lactone found in plants of the Asteraceae family [11,41,44–48] . While it boasts a variety of biological activities including schistosomicidal, [11] trypadocinal, [4,46,49] antimycobacterial, [47] cytotoxic, [47,48,50] genotoxic [51] and anti‐hyperuricemic, [52] the exact mode of action behind goyazensolide and its related furanoheliangolides remained elusive.…”
Section: Resultsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Goyazensolide is a natural sesquiterpene lactone found in plants of the Asteraceae family [11,41,44–48] . While it boasts a variety of biological activities including schistosomicidal, [11] trypadocinal, [4,46,49] antimycobacterial, [47] cytotoxic, [47,48,50] genotoxic [51] and anti‐hyperuricemic, [52] the exact mode of action behind goyazensolide and its related furanoheliangolides remained elusive.…”
Section: Resultsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Taxifolin ( 24) is a well-known natural compound, and blumeatin A (23) was described in Blumea balsamiferia. 30 The vanilloid isomer 22 occurs as trace component (5 mg/kg) besides HED (1) in Lychnophora granmongolense ("Brazil arnica"), 31 whereas the isomer 25, which is related to the flavanone sterubin, was also found in Blumea balsamiferia. 32 Dihydromyricetine or ampelopsin (26) was found in Ampelopsis cantoniensis.…”
Section: ■ Results and Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The NOEDIFF experiments confirmed all relative stereochemistry for each structure and some previously ambiguous carbon assignments were also clarified. C NMR data for centratherin (2). 500MHz, CDCl 3 …”
Section: Resultsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.