A study of the inclusion complex of bioactive thiadiazole derivative with 2‑hydroxypropyl‑β‑cyclodextrin: Preparation, characterization and physicochemical properties

Cannabidiol/hydroxypropyl-β-cyclodextrin inclusion complex: structure analysis, release behavior, permeability, and bioactivity underin vitrodigestion

“…The encapsulation enthalpy was determined by two aspects: endothermic reaction due to dehydration of the guest molecule and fracture of the hydrogen bonding interactions in CDs cavity respectively, and exothermic process because of the formation of interactions between the entrapped molecule and CD. 25 The energy released when CBD formed the IC with HP-b-CD was relatively small, so the process was endothermic. Furthermore, the entropy value is mainly determined by the destruction of the guest molecule and the decrease in degrees of transitional and rotational freedom.…”

Research Progress on Synthesis and Application of Cyclodextrin Polymers

“…For example, CDs can improve the solubility of the guest [ 28 , 29 , 30 ]. Their synthesis methods include the saturated aqueous solution method, the ultrasonic method, grinding, colloid milling, freeze drying, and spray drying [ 31 , 32 , 33 ]. There are various synthetic methods that are widely used in the field of biomedicine and their applications will be explained in detail below.…”

Preparation and Characterization of Indomethacin Supramolecular Systems with β-Cyclodextrin in Order to Estimate Photostability Improvement

“…To further confirm the 1:1 stoichiometry of the formed complexes between I β-CD in water in the ground and excited states, a Job's plot procedure was used be seen in the insert of Figure 1C,D, the curve maximum falls at about 0.5, which c the 1:1 stoichiometry in the ground and excited states. In the study of host-guest supramolecular chemistry, absorption spectra we larly used to verify IC formation [35,36]. Characteristics of complexes were also pe through the use of such methods as DSC [37], XRD [38,39] and NMR [40,41], with constants also determined [16,42].…”

“…The changes in the UV-Vis sp IND in the PM and IC samples after photodegradation are presented in Figures respectively. In the study of host-guest supramolecular chemistry, absorption spectra were regularly used to verify IC formation [35,36]. Characteristics of complexes were also performed through the use of such methods as DSC [37], XRD [38,39] and NMR [40,41], with binding constants also determined [16,42].…”