A Study of the Effectiveness of Two Common Fluoroquinolones on Mycobacterial Strains Isolated From Patients

Abstract

Background and objectives: Investigation and study of second-line drugs effects on mycobacterial strains has been of great importance due to prevalence of drug resistance especially multi-drug resistance (MDR) in Mycobacterium tuberculosis (MTB) strains in the recent years. The objective of this research was to determine drug sensitivity of Mycobacterium tuberculosis and mycobacteria other than tubercle bacilli (MOTT) strains to the two common second-line anti-mycobacterial fluoroquinolones, i.e. ofloxacin (OFL) and ciprofloxacin (CIP).