A Study of the Correlation of Perfusion Parameters in High‐Resolution GRASP MRI With Microvascular Density in Lung Cancer

Chen, Lihua; Zeng, Xian‐Chun; Wu, You-Li; Xi, Yan; Huang, Xuequan; Chen, Hui; Zhang, Jiuquan; Wang, Jian; Feng, Li

doi:10.1002/jmri.26340

Cited by 11 publications

(8 citation statements)

References 33 publications

(42 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to Heacock et al, GRASP DCE-MRI has a near comparable performance with conventional VIBE imaging for breast lesion evaluation, which is also in line with our findings [17]. Additionally, functional assessment such as the evaluation of tumour angiogenesis in lung cancer was shown by Chen et al [20]. Extended benefits like the functional assessment for rectal cancer, as shown by Attenberger et al, could be feasible for the head and neck region as well and should be evaluated in further studies with histopathological correlations [21].…”

Section: Discussionsupporting

confidence: 91%

Achieving high spatial and temporal resolution with perfusion MRI in the head and neck region using golden-angle radial sampling

et al. 2020

View full text Add to dashboard Cite

Objectives Conventional perfusion-weighted MRI sequences often provide poor spatial or temporal resolution. We aimed to overcome this problem in head and neck protocols using a golden-angle radial sparse parallel (GRASP) sequence. Methods We prospectively included 58 patients for examination on a 3.0-T MRI using a study protocol. GRASP (A) was applied to a volumetric interpolated breath-hold examination (VIBE) with 135 reconstructed pictures and high temporal (2.5 s) and spatial resolution (0.94 × 0.94 × 3.00 mm). Additional sequences of matching temporal resolution (B: 2.5 s, 1.88 × 1.88 × 3.00 mm), with a compromise between temporal and spatial resolution (C: 7.0 s, 1.30 × 1.30 × 3.00 mm) and with matching spatial resolution (D: 145 s, 0.94 × 0.94 × 3.00 mm), were subsequently without GRASP. Instant inline-image reconstructions (E) provided one additional series of averaged contrast information throughout the entire acquisition duration of A. Overall diagnostic image quality, edge sharpness and contrast of soft tissues, vessels and lesions were subjectively rated using 5-point Likert scales. Objective image quality was measured as contrast-to-noise ratio in D and E. Results Overall, the anatomic and pathologic image quality was substantially better with the GRASP sequence for the temporally (A/B/C, all p < 0.001) and spatially resolved comparisons (D/E, all p < 0.002 except lesion edge sharpness with p = 0.291). Image artefacts were also less likely to occur with GRASP. Differences in motion, aliasing and truncation were mainly significant, but pulsation and fat suppression were comparable. In addition, the contrast-to-noise ratio of E was significantly better than that of D (pD-E < 0.001). Conclusions High temporal and spatial resolution can be obtained synchronously using a GRASP-VIBE technique for perfusion evaluation in head and neck MRI. Key Points • Golden-angle radial sparse parallel (GRASP) sampling allows for temporally resolved dynamic acquisitions with a very high image quality. • Very low-contrast structures in the head and neck region can benefit from using the GRASP sequence. • Inline-image reconstruction of dynamic and static series from one single acquisition can replace the conventional combination of two acquisitions, thereby saving examination time.

show abstract

Section: Discussionsupporting

confidence: 91%

Achieving high spatial and temporal resolution with perfusion MRI in the head and neck region using golden-angle radial sampling

et al. 2020

View full text Add to dashboard Cite

show abstract

“…While the protocol of the current study involved only GRASP-VIBE for high temporal resolution, GRASP-VIBE can also be acquired with high spatial resolution. Finally, the functional application of GRASP-VIBE in evaluating tumor angiogenesis has also been previously investigated in lung cancer, 17 rectal cancer, 18 and parotid neoplasms, 19 proving its 4D imaging characteristics.…”

Section: Discussionmentioning

confidence: 99%

Intraindividual Comparison between the Contrast-Enhanced Golden-Angle Radial Sparse Parallel Sequence and the Conventional Fat-Suppressed Contrast-Enhanced T1-Weighted Spin-Echo Sequence for Head and Neck MRI

Hur

Choi

Yoon

et al. 2021

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

BACKGROUND AND PURPOSE:The golden-angle radial sparse parallel-volumetric interpolated breath-hold (GRASP-VIBE) sequence is a recently introduced imaging technique with high resolution. This study compared the image quality between conventional fatsuppressed T1-weighted TSE and GRASP-VIBE after gadolinium enhancement in the head and neck region.MATERIALS AND METHODS: Data from 65 patients with clinical indications for head and neck MR imaging between September 2020 and January 2021 were retrospectively reviewed. Two radiologists assessed the overall image quality, overall artifacts, and image conspicuities in the oropharynx, hypopharynx, and cervical lymph nodes according to 5-point scores (best score: 5). Interobserver agreement was assessed using weighted k statistics. The SNR and contrast-to-noise ratio were calculated and compared between the 2 sequences using a paired Wilcoxon signed rank test.

show abstract

“…Newer techniques allowing for faster imaging, including those using a radial acquisition of k ‐space and compressed sensing (eg, GRASP for Siemens), provide an improved means of obtaining images suitable for DCE in the thorax by increasing temporal resolution and decreasing the effects of motion . While temporal resolution is variable, depending on the desired application and the sequences used, temporal resolution of ≤3 seconds is required to reliably obtain quantitative parameters for estimating neoangiogenesis . Motion correction software may be needed, particularly for high temporal resolution applications .…”

Section: Building Blocksmentioning

confidence: 99%

“…64 While temporal resolution is variable, depending on the desired application and the sequences used, temporal resolution of ≤3 seconds is required to reliably obtain quantitative parameters for estimating neoangiogenesis. 27,64,65 Motion correction software may be needed, particularly for high temporal resolution applications. [58][59][60][61][62][63] Ultimately, DCE data can be used with DWI for a "multiparametric" approach, which allows for characterization of lesions before and after treatment.…”

Section: Functional Sequencesmentioning

confidence: 99%

Building blocks for thoracic MRI: Challenges, sequences, and protocol design

Raptis

Ludwig

Hammer

et al. 2019

Magnetic Resonance Imaging

View full text Add to dashboard Cite

Thoracic MRI presents important and unique challenges. Decreased proton density in the lung in combination with respiratory and cardiac motion can degrade image quality and render poorly executed sequences uninterpretable. Despite these challenges, thoracic MRI has an important clinical role, both as a problem‐solving tool and in an increasing array of clinical indications. Advances in scanner and sequence design have also helped to drive this development, presenting the radiologist with improved techniques for thoracic MRI. Given this evolving landscape, radiologists must be familiar with what thoracic MR has to offer. The first step in developing an effective thoracic MRI practice requires the creation of efficient and malleable protocols that can answer clinical questions. To do this, radiologists must have a working knowledge of the MR sequences that are used in the thorax, many of which have been adapted from use elsewhere in the body. These sequences can be broadly divided into three categories: traditional/anatomic, functional, and cine based. Traditional/anatomic sequences allow for the depiction of anatomy and pathologic processes with the ability for characterization of signal intensity and contrast enhancement. Functional sequences, including diffusion‐weighted imaging, and high temporal resolution dynamic contrast enhancement, allow for the noninvasive measurement of tissue‐specific parameters. Cine‐based sequences can depict the motion of structures in the thorax, either with retrospective ECG gating or in real time. The purpose of this article is to review these categories, the building block sequences that comprise them, and identify basic questions that should be considered in thoracic MRI protocol design. Level of Evidence: 5 Technical Efficacy Stage: 3 J. Magn. Reson. Imaging 2019;50:682–701.

show abstract

A Study of the Correlation of Perfusion Parameters in High‐Resolution GRASP MRI With Microvascular Density in Lung Cancer

Cited by 11 publications

References 33 publications

Achieving high spatial and temporal resolution with perfusion MRI in the head and neck region using golden-angle radial sampling

Achieving high spatial and temporal resolution with perfusion MRI in the head and neck region using golden-angle radial sampling

Intraindividual Comparison between the Contrast-Enhanced Golden-Angle Radial Sparse Parallel Sequence and the Conventional Fat-Suppressed Contrast-Enhanced T1-Weighted Spin-Echo Sequence for Head and Neck MRI

Building blocks for thoracic MRI: Challenges, sequences, and protocol design

Contact Info

Product

Resources

About