A Study of the Association of Glucosinolates to Rapeseed Meal-Induced Hemorrhagic Liver in Poultry and the Influence of Supplemental Vitamin K

Abstract

Pepes, A., CelrerLl, L. D. eNo CeNsrrlr_o, p. E. 1979. A study of the association of glucosinolates to rapeseed meal-induced hemorrhagic liver in poultry and the influence of supplemental vitamin K. Can. J. Anim. Diets were formulated to contain variable amounts of intact glucosinolates (IG) and vanous aglucones: I-cyano-2-hydroxy-3-butene (cHB); 5-vinyloxazolidine-2-thione (OZT); isothiocyanates (NCS); and inorganic thiocyanate (SCN) to study the relation of glucosinolates to rapeseed meal (RSM)-induced hemorrhagic liver (HL) in laying hens.The influence of supplementat vitamin K in alleviating the HL effect was also studied using broiler chickens and SCWL hens of an experimental strain.

Rapeseed meal‐glucosinolates and their antinutritional effects Part 4. Goitrogenicity and internal organs abnormalities in animals

“…Poultry Due to differences in the lifespan and in the periods of taking diets with RSM inclusion, the goitrogenic activity of glucosinolates is a less significant problem in broiler chickens but can be considerable in laying hens. The latter case was demonstrated in many earlier works, including PAPAS et al [77,781. These authors showed a clear antinutritional activity of intact glucosinolates, while l-cyano-2-hydroxy-3-butene present in diets at relatively high concentrations (0.5 and 0.8%) did not exert adverse symptoms [including thyroid hypertrophy and disfunction).…”

“…The latter case was demonstrated in many earlier works, including PAPAS et al [77,781. These authors showed a clear antinutritional activity of intact glucosinolates, while l-cyano-2-hydroxy-3-butene present in diets at relatively high concentrations (0.5 and 0.8%) did not exert adverse symptoms [including thyroid hypertrophy and disfunction).…”

“…There are no reports of gross liver enlargement in dairy cattle, however calves fed rapeseed exhibited increases in liver weight ranging from 11 -38% over control animals [77, 1151. These changes were not related to glucosinolate intake; no histological abnormalities were observed [77] and the effects were partially offset by dietary administration of L-thyroxine [115]. Significantly higher liver weights were observed in steers fed kale [4] but conflicting results have been published for lambs fed stem kale/rape.…”

ALTERATION OF GLUCOSINOLATE CONTENT, PATTERN, AND MUTAGENICITY OF CABBAGE (BRASSICA OLERACEA) GROWN ON MUNICIPAL SEWAGE SLUDGE—AMENDED SOIL

“…The content of toxic heavy metals and organic compounds, of primarily industrial origin, in municipal sewage sludges has led to considerable research to evaluate the possible effects on food safety of the applica-Glucosinolates are important secondary plant metabolites present in all Brassica vegetables (Kjaer 1973;Larsen 1981). At relative high intake levels they have been associated with goiter and allergic dermatitis in humans and a myriad of toxic effects in animals (Van Etten et al 1969;Singh 1970;Ahmad and Muztar 1971;Mitchell and Jordan 1974;Yamashiro et al 1975Yamashiro et al ,1977David 1976;Terry et al 1976;Campbell et al 1977;Papas et al 1977Papas et al , 1979Umemura et al 1977;Yamashiro and Bast 1978;Campbell and Smith 1979;Ibrahim and Hill 1980;Nishie and Daxenbichler 1980). Glucosinolates are also the most important flavor components of the Brussica vegetables (MacLeod 1976).…”

Choline, Niacin and Thiamine Supplementation of Canola and Soybean Protein Diets Fed to Broilers to 6 wk of Age

“…), leg problems (Seth and Clandinin 1973), egg taint (Goh et al 1979), and liver hemorrhage (Papas et al 1979). Although the concentration of choline is high in canola meal (March and MacMillan 1980) it appears thar rhe availability of this vitamin may be in question (March and MacMillan 1980;March 198 1).…”