A Study of Thalamo-Cortical Relations

Input-specific effects of acetylcholine on sensory and intracortical evoked responses in the “barrel cortex” in vivo

“…Neocortical activity is influenced by stimulus repetition whereby stimulation of nuclei within the dorsal thalamus produces frequency-dependent responses in the neocortex (Dempsey & Morison, 1942a, 1942bMorison & Dempsey, 1942 Connors, 1996b).…”

Cross-modal plasticity in the human thalamus: evidence from intraoperative macrostimulations

“…The first operation (CLT, for CL-thalamotomy; Fig. 1a) was performed in the three groups of patients based on the recruiting properties of CL neurons through "diffuse" projections to the cortex (Morison and Dempsey 1942;Jones and Leavitt 1974;Macchi and Bentivoglio 1986) and on the presence of abnormal low threshold calcium spikes (LTS) bursting activities in these patients (Jeanmonod et al 1996). The second operation (PTT, for pallidothalamic tractotomy, Fig.…”

“…The thalamus has been from the beginning an important target for neurogenic pain and motor disorders, and both medial and lateral nuclei were explored (Sano et al, 1966;Cooper et al 1969;Goldmann et al 1992;Gybels et al 1993;Yamashiro and Tasker 1994;Burchiel 1995;Velasco et al 1995;Benabid et al 1996;Abosch and Lozano 2003). In the medial thalamus, the intralaminar nuclei, including the central lateral and centre médian nuclei, were chosen in neurogenic pain for their connections with the medial spinothalamic tract, and more generally for their recruiting properties through "diffuse" projections to the cortex (Morison and Dempsey 1942;Mehler 1966Mehler , 1974Sano et al 1966;Jones and Leavitt 1974;Macchi and Bentivoglio 1986;Jeanmonod et al 1996Jeanmonod et al , 2001a. With recent reappraisal of the anatomical boundaries of the CL, particularly its posterior extension (Hirai and Jones 1989;Morel et al 1997, Morel 2007) and on the basis of its extensive projections to the cortex and thalamic reticular nucleus, this nucleus has been re-updated as a neurosurgical target, alone or in combination with others, for surgical interventions in several functional disorders (Jeanmonod et al 1996(Jeanmonod et al , 2001a(Jeanmonod et al ,b, 2003.…”

Mecanismos do sono e da vigília

“…47 e Dempsey e Morison 18,19 descobriram que a estimulação iterativa a baixa freqüência (8 a 12 Hz) de certos núcleos talâmicos causava o aparecimento, em várias regiões do córtex cerebral, de potenciais cuja característica principal era a de aumentarem de amplitude com a progressão dos estímulos.…”