A study of metastatic lesions of lymph nodes by fine needle aspiration cytology

Meena, Pratibha; Mishra, Ranu Tiwari

doi:10.18203/2320-6012.ijrms20174589

Cited by 3 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cervical region was most common site for metastatic lesions were 84.81%. These results were near comparable with Pratibha et al [14] in which 75.2%. lymphoma cases were 3.2%.…”

Section: Discussionsupporting

confidence: 91%

Study of lymphnode lesions by fine needle aspiration cytology and histopathology: A study of 125 cases

Patel¹,

Patel²

2019

Trop J Pathol Microbiol

View full text Add to dashboard Cite

Background: Fine needle aspiration cytology (FNAC) is a simple and rapid diagnostic technique and because of early availability of results, simplicity, minimal trauma and complication, the aspiration cytology is now considered as a valuable diagnostic aid and is gaining popularity. It also helps in giving proper direction for appropriate investigations. Objectives: To find out number of cases where FNAC of the lymph nodes picked up an unsuspected malignancy and to correlate the cytological findings with the histopathological findings in cases where lymph node biopsy is done. Methodology: It was a prospective study done on patient who presented with lymphadenopathy to various departments and referred to pathology department. The aspirate was collected from the enlarged lymphnodes using standard procedure with proper aseptic condition. The aspirate was examined for the amount and nature of the aspirated material, and then several smears were prepared. Smears were immediately fixed in 95% ethyl alcohol, and these smears were examined using various stains like haematoxylin and eosin stain, PAS stain also MGG's stain and Ziehl Neelsen stain. Observations: out of total 125 patients, 91 (73.60%) were Male patients and 34 (26.40%) were Female patients with M:F ratio of 2.79:1 with Male predominance. Distributions of all lymph node lesions shows cervical site i.e. 97 (77.6%) followed by inguinal i.e. 14 (11.2%) and other sites. Among all lymphnode lesions, 66.40% were neoplastic lesions and 33.60% were non-neoplastic lesions. Neoplastic lesions were more common in cervical group and Metastatic squamous cell carcinoma was more common in cervical group. Cytological diagnosis was correlated with histopathology diagnosis in 13.6% cases. Conclusion: FNAC can help not only to differentiate among lymphoma, and metastasis, but also to identify nonspecific reactive lymphadenitis and specific infections such as tuberculosis lymphadenitis. The results are quite encouraging and even more advanced diagnostic tools available, FNAC can still recommended as the initial diagnostic test in the evaluation of superficial lymphadenopathy.

show abstract

“…Cervical region was most common site for metastatic lesions were 84.81%. These results were near comparable with Pratibha et al [14] in which 75.2%. lymphoma cases were 3.2%.…”

Section: Discussionsupporting

confidence: 91%

Study of lymphnode lesions by fine needle aspiration cytology and histopathology: A study of 125 cases

Patel¹,

Patel²

2019

Trop J Pathol Microbiol

View full text Add to dashboard Cite

show abstract

“…This is consistent with many studies. [12][13][14][15] Adenocarcinoma was the next common metastatic malignancy in our study. This was also observed in other studies.…”

Section: Discussionmentioning

confidence: 90%

Role of FNAC in the diagnosis of lymph node malignancies - An institutional experience

Gupta

Gupta²,

Bhardwaj³

2023

ACHR

View full text Add to dashboard Cite

Lymphadenopathy is a sign of underlying infection, primary or metastatic malignancy. Fine-needle aspiration is a simple and reliable tool for its initial investigation. To analyse the cytomorphological features of malignant lymph node lesions and to determine the frequency of different lymph node malignancies. It was an observational, retrospective study conducted in the cytology section of Department of Pathology, Govt. Medical College, Jammu. It included lymph node aspirates that were reported as malignant. May-Grunwald-Giemsa (MGG) and Papanicolaou (PAP) stained smears were examined under light microscope and the cytological features were studied. A total of 97 malignant lymph node aspirates were included in this study. Metastatic malignancy accounted for maximum number of cases (78, 80.4%) followed by lymphoma (19, 19.6%). Squamous cell carcinoma was the most common metastatic malignancy and also the most frequently diagnosed malignant lesion in our study (42, 43.3%). Cervical lymph nodes were the most commonly aspirated lymph nodes.FNAC of lymph nodes is a simple and valuable tool in the diagnosis of lymph node malignancies.

show abstract

Spectrum of Malignant Lesions in the Lymph Node on Fnac in a Tertiary Care Hospital in Himachal Pradesh.

Chandran¹,

Gulati

Sharma

et al. 2022

IJAR

View full text Add to dashboard Cite

Background: Lymphadenopathy, is any abnormal enlargement of the lymph node due to the inltration by the inammatory or the neoplastic cells. This is the most common and may be the only presentation of the patient attending the outpatient department (OPD). Fine needle aspiration cytology (FNAC) is a simple, reliable and rst line OPD investigation in such cases. Material And Methods: It is a retrospective study carried out over a period of 18 months (1/1/2021) to 30/6/2022) in the Department of Pathology, Indira Gandhi Medical College (IGMC) Shimla, a tertiary care hospital of the state. All the cytology cases received in the department were included in the study. Results: Of the total 2870 cases, received in the department of Pathology, 880 (30.6%) cases were from the lymph node. Benign pathology was seen in 645 (73.3%) cases and 235 (26.7%) cases had a malignant lesion. Of these 235 malignant cases, 205 (87.5%) cases were positive for malignancy while 30 (12.8%) cases revealed a hematologic malignancy. Majority of the patients were above 40 years of age. Males contributed to 58.7% cases while 41.3% were females. Cervical lymph node was most common lymph node involved followed by supraclavicular lymph nodes. The squamous cell carcinoma (36.1%) was the most common metastatic lesion followed by adenocarcinoma (28.3%). NHL was more common among the lymphoproloiferative disorders. FNAC is a rapid a Conclusion: nd a fairly reliable test for the diagnosis of metastatic lesion and at the same time giving the clue about the origin of the primary occult malignancy.

show abstract

A study of metastatic lesions of lymph nodes by fine needle aspiration cytology

Cited by 3 publications

References 3 publications

Study of lymphnode lesions by fine needle aspiration cytology and histopathology: A study of 125 cases

Study of lymphnode lesions by fine needle aspiration cytology and histopathology: A study of 125 cases

Role of FNAC in the diagnosis of lymph node malignancies - An institutional experience

Spectrum of Malignant Lesions in the Lymph Node on Fnac in a Tertiary Care Hospital in Himachal Pradesh.

Contact Info

Product

Resources

About