A Study of Medication Adherence and Medication Compliance to Insulin Therapy in Type I and Type II Diabetic Patients

Anju, P R; Siddiq, Abubaker

doi:10.5530/ijopp.11.3.29

Cited by 2 publications

(1 citation statement)

References 2 publications

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“…The Persian version of 8-item MMAS was previously validated in patients with T2DM, including patients who receive insulin [ 16 ]. Moreover, the MMAS questionnaire was used in patients with T1DM in multiple studies to evaluate insulin adherence [ 6 , 8 , 17 – 20 ].…”

Section: Methodsmentioning

confidence: 99%

Associated factors to insulin adherence in type 1 diabetes in Tehran and Karaj, Iran

Fayyaz

Aghamahdi

Noorian

et al. 2022

J Diabetes Metab Disord

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Purpose Type 1 diabetes mellitus (T1DM) is a chronic metabolic disorder, and its prevalence and incidence are increasing globally. Insulin therapy is the basis of T1DM management that can prevent numerous complications. Identifying and resolving the factors involved in patients’ non-adherence can reduce complications, mortality, and economic burden. Methods In this cross-sectional study, a sample of patients with T1DM were included from Alborz and Tehran cities of Iran in 2020. Patients filled the questionnaires consisting of sociodemographic and diabetes characteristics, weight and height measurements, 8-item Morisky Medication Adherence Scale (MMAS), and barriers to insulin therapy. Patients with < six scores of MMAS were considered to have low adherence, while ≥ 6 scores showed moderate/high adherence. Data were analyzed using SPSS, and a P-value of less than 0.05 was considered statistically significant. Results 189 patients with T1DM with a mean (± SD) age of 17.95 (± 10.98) years were enrolled in the study, and 73.5% of patients had moderate/high adherence to insulin therapy. Younger age and owning insurance were significantly associated with being classified in the higher adherence group. The barriers that were significantly associated with non-adherence were forgetting to buy, physician inaccessibility, cost, exhaustion from the long-term injection, forgetfulness, injection site reaction, and rebellion against parents in the < 20 years age group. The main barriers in ≥ 20 years age group were forgetting to buy and insufficient injection instruction. Conclusion The identified barriers to insulin injection would be helpful for policymakers and clinicians to increase insulin adherence among patients with T1DM. Supplementary Information The online version contains supplementary material available at 10.1007/s40200-022-01105-0.

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Section: Methodsmentioning

confidence: 99%

Associated factors to insulin adherence in type 1 diabetes in Tehran and Karaj, Iran

Fayyaz

Aghamahdi

Noorian

et al. 2022

J Diabetes Metab Disord

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Antidiabetic activity of Tephrosia tinctoria in Alloxan induced Diabetic Rats: A Preliminary Study

Samuel

Mahesh

2021

RJPT

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Plant derived products play a vital role in preventing and treating various disease in humans. Tephrosia tinctoria is a plant belonging to the family Leguminosae, found to have antidiabetic and antioxidant activities. The study was aimed to investigate the anti-diabetic and anti-oxidant activity of whole plant of Tephrosia tinctoria in diabetic rats. Alloxan induced model was used to induce Diabetes. The chloroform and ethanolic extracts of Tephrosia tinctoria (CETT and EETT) at the dose of 250 and 500mg/kg b.w were administered orally at single dose per day to diabetic rats. Glipizide 5mg/kg b.w was used as standard drug. The general body weight, insulin level, blood glucose, serum lipid profile, superoxide dismutase, and lipid peroxidation assays were the parameters evaluated in diabetic rats. EETT have better anti-diabetic and anti-oxidant activity than CETT. The protective effects were even confirmed by histopathological studies. These observations show that both the extracts were effective in possessing the significant antidiabetic and antioxidant properties in alloxan induced diabetes.

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A Study of Medication Adherence and Medication Compliance to Insulin Therapy in Type I and Type II Diabetic Patients

Cited by 2 publications

References 2 publications

Associated factors to insulin adherence in type 1 diabetes in Tehran and Karaj, Iran

Associated factors to insulin adherence in type 1 diabetes in Tehran and Karaj, Iran

Antidiabetic activity of Tephrosia tinctoria in Alloxan induced Diabetic Rats: A Preliminary Study

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