A study of malignant lymphomas and leukemias.VII. Lymphogenous leukemia and lymphosarcoma involvement of the lymphatic and hemic bed, with reference to differentiating criteria

Morphology of lymphatic cells and of their derived tumours.

“…When the tissue manifestation of B-CLL is not accompanied by an excess of cells in the blood and/or marrow, the disease has been referred to as well-differentiated, lymphocytic, diffuse ML ; a leukaemic manifestation may appear later (Galton, 1966) or never (Goldberg and Emanuel, 1964). However, the morphology and the surface characteristics of the cells are the same as they are in B-CLL (Huber et al, 1974;Peter et al, 1974;Aisenberg and Long, 1975;Brouet et al, 1975b;Braylan et al, 1976).…”