A Study of Lesions of Upper Respiratory Tract

Abstract

The development of the organ systems are highly regulated in physiological conditions and the development of nose and paranasal sinuses commences in the 3rd week of gestation, when the primordial structures first appear and continues until completion in early adulthood when sinus pneumatization and bony growth have ceased. Their misregulation lead to the development of many cancers and primitive nasal septum Squamous cell carcinoma (SCC) of the upper respiratory tract ranks as the sixth leading cause of cancer worldwide.In the current study, out of 31 cases, maximum cases were found to be moderately differentiated grade amounting to 64.5%, followed by well differentiated grade (22.6%) and poorly differentiated grade (12.9%). The present study also showed that poorly differentiated SCC had higher Ki 67 proliferative index and it could be a useful tool for determining the stages of tumors. Ki 67 proliferative index study of the tumor helps in better understanding of the tumor behavior so as to provide appropriate treatment and thereby increasing the survival rate of the patient.

The Prevalence of upper respiratory tract lesions in pathology department, Beni-Suef University Hospital ( Histopathological and immunohistochemical Evaluation )

“…Among the studied lesions, only 13.9% were neoplastic. Anbukkarasi et al, [1] studied 186 cases and reported findings close to ours but male sex was predominant.…”

“…Our study revealed a significant association between older age categories and neoplastic lesions (p<0.001). That was consistent with Anbukkarasi et al, [1] who showed most of squamous cell carcinoma cases were more than 60 years old (80.6% of 31 patients).…”

“…Demographic data of the participants in our study are demonstrated in table (1). The age of the participants ranged from 2.5 to 83 years with a mean age of 40.8±17.6 years.…”

“…It is also susceptible to infections, tumor-like conditions and true neoplastic conditions. Histopathological evaluation is mandatory to differentiate non-neoplastic lesions from neoplastic masses for effective care and proper management [1].…”

The green and chemical synthesis, and characterization of ZnO nanoparticles by aqueous leaf extract of aloe vera

“…In the present study, the biosynthesis of ZnO NPs from leaf extract of aloe brabadens is miller commonly known as aloe vera belongs to asphodelaceae (liliaceae) family and mostly found in subcontinent of India, dry regions of Africa, Asia, Europe and America was preferred. The gel part of aloe vera leafs are widely used in the preparation of traditional medicines and showed antifungal and skin healing properties [9]. The leaf extracts of aloe vera is rich in vitamins, enzymes, minerals and aminoacids [10].…”