A study of health-related quality of life in pediatric atopic dermatitis

Hossny, Elham; Shousha, Ghada; Wassif, Ghada; Hana, Sylvia M.S.

doi:10.21608/ejpa.2020.117838

Cited by 5 publications

(4 citation statements)

References 31 publications

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“…Another study by Hossny et al found that of 85 children with AD from the children's hospital in Ain Shams University in Egypt, more than half of the children (55.4%) had severely affected QoL, with itching and pain being a primary concern. A statistically significant effect of face eczema on QoL of children was also reported [35,36]. In this study, 84.6% of the children believed that the disease had a great impact on their relationship with friends and play, while this was reported in only 2% by other investigators, highlighting the social stigma that patients may feel.…”

Section: Qol Impactsupporting

confidence: 54%

“…It is burdensome to care for a child with AD because of the special needs of the patient, such as with bathing, wet dressings, topical application, and household-related tasks and responsibilities such as food restrictions, clothing selection, laundry, and house cleaning to avoid potential allergens [36]. This is in addition to the added costs of implementing these lifestyle adjustments [1].…”

Section: Qol Impactmentioning

confidence: 99%

“…Emphasizing the importance of maintaining adequate sleep, adopting a healthy diet, and practicing stress management techniques can have a positive impact on AD symptoms and overall wellbeing. Health education programs can help patients and their families adapt to the different challenges they will face with managing AD [36]. Programs such as eczema schools that involve families, healthcare providers, psychologists, and dieticians can provide extremely helpful information to Arab families regarding coping mechanisms, stress management, and daily care of eczema [32].…”

Section: Patient Education and Carementioning

confidence: 99%

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Burden of Disease and Unmet Needs in the Diagnosis and Management of Atopic Dermatitis in the Arabic Population of the Middle East

Mahmoud

Yosipovitch

Attia

2023

JCM

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Atopic dermatitis (AD) affects diverse ethnic groups with significant disparities in prevalence, disease progression, clinical outcomes, and access to care. There are limited data on AD in the Arabic population of the Middle East, yet there is a substantial economic and psychosocial burden of AD in this region with a large unmet need with regards to disease management that is critical to address. There is a trend of increasing prevalence of AD in the Arab Middle East; however, due to the large environmental, socioeconomic, and sociocultural heterogeneity of this region, prevalence varies greatly across and within countries. Similarly, clinical differences in disease presentations exist across the region, although data are limited. In this review, we will present clinical phenotypes of AD common in different regions of the Arab Middle East, and data on prevalence, genetic variations, and challenges of treatment. Further studies exploring molecular biomarkers, genetic polymorphisms, immune factors, and the microbiome of patients in the region will help to elucidate the mechanism behind ethnic differences in AD in this population as well as to understand susceptibilities and treatment response.

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Section: Qol Impactsupporting

confidence: 54%

Section: Qol Impactmentioning

confidence: 99%

Section: Patient Education and Carementioning

confidence: 99%

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Burden of Disease and Unmet Needs in the Diagnosis and Management of Atopic Dermatitis in the Arabic Population of the Middle East

Mahmoud

Yosipovitch

Attia

2023

JCM

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“…The disease tends to manifest more in dry weather [ 9 , 10 ]; therefore, the burden may vary according to the climate of each country. The burden of AD in the Middle East and Africa has been discussed in a recent literature review [ 11 ], and other reviews have estimated its prevalence or burden in specific cities [ 12 , 13 ]; however, to our knowledge, this is the first study to quantify the burden of the disease in adults and adolescents in specific countries in the region. Country-specific burden data are essential to allow decision-makers to make evidence-based decisions and efficiently allocate the available resources.…”

Section: Introductionmentioning

confidence: 99%

Humanistic and Economic Burden of Atopic Dermatitis for Adults and Adolescents in the Middle East and Africa Region

Elezbawy¹,

Fasseeh²,

Fouly³

et al. 2022

Dermatol Ther (Heidelb)

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The Effectiveness of Early Food Introduction in Preventing Childhood Allergic Diseases: Protocol for a Systematic Review and Meta-Analysis

Abdullah¹,

Muhamad²,

Ghani³

et al. 2023

JMIR Res Protoc

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Background Allergic diseases affect around 40% of the pediatric population worldwide. The coexistence of asthma, allergic rhinitis, eczema, and food allergy renders allergy treatment and prevention challenging. Infant feeding strategies recommend avoiding allergenic foods to prevent allergy development and anaphylaxis. However, recent evidence suggests that early consumption of food allergens during weaning in infants aged 4-6 months could result in food tolerance, thus reducing the risk of developing allergies. Objective The aim of this study is to systematically review and carry out a meta-analysis of evidence on the outcome of early food introduction for preventing childhood allergic diseases. Methods We will conduct a systematic review of interventions through a comprehensive search of various databases including PubMed, Embase, Scopus, CENTRAL, PsycINFO, CINAHL, and Google Scholar to identify potential studies. The search will be performed for any eligible articles from the earliest published articles up to the latest available studies in 2023. We will include randomized controlled trials (RCTs), cluster RCTs, non-RCTs, and other observational studies that assess the effect of early food introduction to prevent childhood allergic diseases. Results Primary outcomes will include measures related to the effect of childhood allergic diseases (ie, asthma, allergic rhinitis, eczema, and food allergy). PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines will be followed for study selection. All data will be extracted using a standardized data extraction form and the quality of the studies will be assessed using the Cochrane Risk of Bias tool. A summary of findings table will be generated for the following outcomes: (1) total number of allergic diseases, (2) rate of sensitization, (3) total number of adverse events, (4) improvement of health-related quality of life, and (5) all-cause mortality. Descriptive and meta-analyses will be performed using a random-effects model in Review Manager (Cochrane). Heterogeneity among selected studies will be assessed using the I2 statistic and explored through meta-regression and subgroup analyses. Data collection is expected to start in June 2023. Conclusions The results acquired from this study will contribute to the existing literature and harmonize recommendations for infant feeding with regard to the prevention of childhood allergic diseases. Trial Registration PROSPERO CRD42021256776; https://tinyurl.com/4j272y8a International Registered Report Identifier (IRRID) PRR1-10.2196/46816

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A study of health-related quality of life in pediatric atopic dermatitis

Cited by 5 publications

References 31 publications

Burden of Disease and Unmet Needs in the Diagnosis and Management of Atopic Dermatitis in the Arabic Population of the Middle East

Burden of Disease and Unmet Needs in the Diagnosis and Management of Atopic Dermatitis in the Arabic Population of the Middle East

Humanistic and Economic Burden of Atopic Dermatitis for Adults and Adolescents in the Middle East and Africa Region

The Effectiveness of Early Food Introduction in Preventing Childhood Allergic Diseases: Protocol for a Systematic Review and Meta-Analysis

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