A study of Etiological Pattern in an Epidemic of Acute Febrile Illness During Monsoon in a Tertiary Health Care Institute of Uttarakhand, India

Abstract

Background: Many parts of India are endemic for the dengue, malaria, typhoid and scrub typhus infections. The relative contribution of these illnesses in an outbreak of acute febrile illness is not known in this region.

Scrub Typhus in a Tertiary Care Hospital in North India

“…Nearly one-fourth of our patients presented with altered sensorium, similar to other studies. [12][13][14][15][16][17][18][19][20][21][22] The pathognomonic eschar was present in 14% patients (Table 3), a figure considerably higher than a previous study from the Himalayan region (9.5% patients), but lesser than that reported from south India (43.5%) and Jeju Island in South Korea (75.8%). 26,28,29 This variation in the presence of eschar may be explained by the geographic distribution of different strains of the organism.…”

Etiological Spectrum and Prevalence of Acute Undifferentiated Febrile Illness (AUFI) in Fever Cases Attending our Tertiary Care Centre

“…Typhoid was the commonest cause of AUFI in 28(24.14%) followed by Dengue 12(10.35%). The present study revealed that Typhoid and Dengue were the common causes of AUFI followed by Malaria 6(5.17%), and scrub typhus 2(1.72%), as observed in the previous studies by Thangarasu et al, (2011), Mittal et al, (2015, Singh et al, (2014), Anugrah Chrispal et al, (2010), Rani et al, (2016) and Gopalakrishnan et al, (2013) where the most common causes of AUFI were dengue, Typhoid, Malaria and scrub typhus. In the present study there were 63(54.31%) patients with undiagnosed febrile illness, their clinical outcomes were studied.…”

“…Dengue is one of the most common causes of AUFI in India and it is documented in many studies from north and south India like Mittal et al, (2015), Singh et al, (2014), Rani et al, (2016), Neelushree et al, (2015). Dengue was identified in 12 cases and it was associated with joint pain, bleeding and thrombocytopenia.…”

Study of Clinical Profile of Acute Undifferentiated Fever in a Tertiary Care Hospital

“…where as common clinical sign were hepatomegaly 29% and splenomegaly 26% but a study done in Thailand reported common symptoms of acute undifferentiated fever as headache, myalgia and vomiting. 10 In present study typhoid fever (41%) was the commonest cause of acute undifferentiated fever followed by malaria (23%),dengue fever (20%),urinary tract infection (5%), scrub typhus (3%) and chikungunya (1%).A study conducted by Singh et al 11 from the region of Uttarakhand shows that dengue, malaria and Typhoid are the most common aetiological agent of acute febrile illness.In countries like Thailand, Malaysia and Nepal -dengue fever, malaria, scrub typhus, leptospirosis and enteric have been identified as main causes of acute undifferentiated fever. 12 Chrispal et al 13…”