A study of diagnostic criteria for endometrial cytology

Yoshida, Shioko; Kusunoki, N.; Ishiyama, Koji; Sugiyamada, Takao; Norimatsu, Yoshiaki; Shimizu, Keiko; Tsukazaki, Katsumi; Ito, Ryoya; Hasegawa, Toshihiko

doi:10.5795/jjscc.47.227

Cited by 3 publications

(1 citation statement)

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“…Moreover, their accuracy for detecting endometrial carcinoma and its precursor lesion is not satisfactory. In contrast, our diagnostic criteria have been independently assessed by other Japanese institutions, 14 , 15 which reported increased diagnostic accuracy with their use. With all of the laboratories in this study, we achieved an extremely high diagnostic accuracy, as the cytological report focused on the necessity or otherwise of doing an endometrial biopsy.…”

Section: Discussionmentioning

confidence: 99%

New diagnostic reporting format for endometrial cytology based on cytoarchitectural criteria

Yanoh¹,

Norimatsu

Hirai

et al. 2009

Cytopathology

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Objective:The aim of this study was to develop a new reporting format for endometrial cytology that would standardize the diagnostic criteria and the terminology used for reporting.Methods:In previous studies, cytoarchitectural criteria were found to be useful for the cytological assessment of endometrial lesions. To apply these criteria, an appropriate cytological specimen is imperative. In this article, the requirements of an adequate endometrial cytological specimen for the new diagnostic criteria are first discussed. Then, the diagnostic criteria, standardized on a combination of conventional and cytoarchitectural criteria, are presented. Third, terminology that could be used, not only for reporting the histopathological diagnosis, but also for providing better guidance for the gynaecologist to determine further clinical action, is introduced. The proposed reporting format was investigated using endometrial cytology of 58 cases that were cytologically underestimated or overestimated compared to the histopathological diagnosis made on the subsequent endometrial biopsy or surgical specimens.Results:Of the 58 cases, 12 were reassessed as being unsatisfactory for evaluation. Among the remaining 46 cases, 25 of the 27 cases, which had been underestimated and subsequently diagnosed as having endometrial carcinoma or a precursor stage on histopathological examination,were reassessed as recommended for endometrial biopsy. On the other hand, 19 cases overestimated by cytology were all reassessed as not requiring biopsy.Conclusions:The reporting format for endometrial cytology proposed in this article may improve diagnostic accuracy and reduce the number of patients managed inappropriately.

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Section: Discussionmentioning

confidence: 99%