A study of cytological pattern of cervical papanicolaou smears in western Rajasthan, India

Rawat, Kiran; Rawat, Narendra; Mathur, Navgeet; Mathur, Medha; Chauhan, Nitesh; Tinna, Rajat; Kakkar, Rahul

doi:10.18203/2320-1770.ijrcog20163009

Cited by 8 publications

(8 citation statements)

References 9 publications

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“…Our study was seen to be in accordance with the study conducted by Atla B et al 8 and Balaha M H et al 9 whereas the studies conducted by Das et al, 10 Pun RG et al 11 and Rawat K et al 12 showed maximum number of smears having negative for intraepithelial lesion or malignancy with lesser prevalence of inflammatory, intraepithelial lesion and frank carcinomas. The discrepancies with these studies could be due to the sample size which were comparatively higher in these studies and also the study period in the study conducted by Rawat et al and Pun RG et al were longer than the present study.…”

Section: Discussionsupporting

confidence: 92%

Cytomorphological spectrum of cervical smears in a tertiary hospital

Ashwini¹,

Ramu²,

Bevinakatti³

et al. 2020

ACHR

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Cervical cancer is one of the leading causes of mortality and morbidity in women worldwide. Invasive cervical carcinomas are preceded by a stage in which the abnormal cells are confined to the epithelium (Intraepithelial stage). Women can be routinely screened for intraepithelial stage with cervical cytology smears and hence invasive stage can be prevented by early diagnosis. Cervical cytology smears also an useful tool in aiding the diagnosis of infectious and inflammatory conditions of the cervix. Objectives: To evaluate the cytomorphological spectrum of cervical smears referred to a tertiary hospital. Materials and Methods: It is a retrospective observational study. Clinical data and pap smear cytology reports were obtained from the archives during the period of May 2018-May 2019(1 year study). All smears were reported as per "Bethesda system of reporting cervical cytology " 2001. Results : A total of 1241 cases were examined. The age group of patients ranged between 18yrs to 75 yrs. A total of 1203 cases (97%) were reported as Negative for intraepithelial lesions/malignancy, out of which 124 cases(0.1%) showed vaginal candidiasis, 56 cases (0.05%) were reported as Trichomonas vaginalis infection, 321 cases (0.26%) as Bacterial vaginosis, 1 case of HSV infection associated changes, 67 cases(0.05%) were reported as inflammatory smears. 38 cases showed abnormality, out of which 29 cases were of ASC-US,3 cases of LSIL, 3 cases were reported as HSIL, 2 cases as Squamous cell carcinoma and 1 case with adenocarcinoma cervix. Conclusion: Cervical inflammatory lesions (including infections) and neoplastic lesions (includes intraepithelial and epithelial malignancies) can be diagnosed by Cervical cytological smears.

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Section: Discussionsupporting

confidence: 92%

Cytomorphological spectrum of cervical smears in a tertiary hospital

Ashwini¹,

Ramu²,

Bevinakatti³

et al. 2020

ACHR

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“…Proportion of inadequate samples were 4.18 % in our set up while two separate studies done by Rawat K et al (16.1%) and Gupta S et al reports similar findings. 14,15 The unsatisfactory rate is an important quality assurance indicator in cervical cytology as it identifies women who are being inadequately screened.…”

Section: Discussionmentioning

confidence: 99%

Study of cytological pattern of pap smears and detection of cervical cancers in Gujarat, India

Patel¹,

Savjiani²

2020

ACHR

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Cervical cancer is one of the leading causes of morbidity and mortality. It can be preventable and diagnosed early with adequate and repetitive cytological screening by pap test. The conventional cervical cytological screening is the most common technique used throughout the world. Objective: To characterize the age and pattern of Pap smear abnormalities in a population of Gujarat, India. Materials and Methods: A retrospective study was conducted at tertiary care hospital of Gujarat India. All previously collected pap smear from 2011 -2014 was evaluated for cytological pattern and during this duration total 1100 pap smear was evaluated. Results: The mean age of patients with abnormal smears was 37.5 years. The mean parity was 4.34. There were 46 (4.18%) unsatisfactory smears and 1054(95.82%) adequate smears. Atypical squamous cell of undetermined significance(ASCUS), low grade squamous intraepithelial lesion (LSIL), and high grade squamous intraepithelial lesion (HSIL) were reported in 69 (6.54%), 111(10.53%), and 55 (5.21%) women respectively. Atypical glandular cell and squamous cell carcinoma were reported in 10 (0.94%) and 5 (0.47%) respectively Conclusion: This study emphasized the importance of Pap smears screening for early detection of premalignant and malignant lesions of cervix. Pap smear testing is a very useful, simple, economical and safe tool to detect preinvasive cervical epithelial lesions. Hence, on a routine basis, every woman above the age of 30 must be subjected to Pap smear and this must be continued even in post-menopausal period as most of patients with epithelial abnormalities in our study falls in this group.

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“…Various studies suggest prevalence rates of abnormal epithelial changes ranging from 1.4-7.8% in India. 9,10 Kiran Rawat et al, reported 3.2% cases as showing abnormal epithelial changes in conventional Pap smear study. 9 There were 24 cases were reported as ASC (atypical squamous cells (ASCUS+ASC-H) with positive histological concordance in only 1 case.…”

Section: Discussionmentioning

confidence: 99%

“…9,10 Kiran Rawat et al, reported 3.2% cases as showing abnormal epithelial changes in conventional Pap smear study. 9 There were 24 cases were reported as ASC (atypical squamous cells (ASCUS+ASC-H) with positive histological concordance in only 1 case. On the other hand, in the present study, 11 cases were reported as HSIL and SCC with positive histological concordance for all cases for which the data was available.…”

Section: Discussionmentioning

confidence: 99%

A prospective study of cervical lesions diagnosed by liquid based cytology in Western Rajasthan, India population

et al. 2019

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Background: Carcinoma cervix is the second most common malignancy of women in India after breast cancer. The present study was conducted to determine the spectrum of cervical lesions by liquid-based cytology in Western Rajasthan population.Methods: It is a Prospective study on 1087 cervical samples carried over a period of 1 year. Cervical samples were taken and processed by SurePath™ LBC.Results: Of total 1087 cases 959 were negative for intraepithelial lesion or malignancy (88.22%). 88 cases (8.09%) were reported as unsatisfactory. Among the non- neoplastic cases- bacterial vaginosis was reported in 209 cases (21.8%), Candida in 77 cases (8.02%), both Candida and bacterial vaginosis in 12 cases (1.25%), reactive cellular changes in 193 cases (20.12%), and Trichomonas vaginalis in 01 case. Among pre-malignant and malignant lesions, 40 cases (4.17%) the distribution was as follows-atypical squamous cells of undetermined significance 16(1.67%), atypical squamous cell-cannot rule out high grade 08 cases (0.83%), Low grade squamous intraepithelial lesion 04 cases (0.42%), high grade squamous intraepithelial lesion 07 cases (0.73%), Atypical glandular cell favoring neoplastic 01 case (0.15%), and squamous cell carcinoma 04 cases (0.42%). Histopathological co-relation of premalignant and malignant lesions was further studied.Conclusions: Liquid based cytology is an effective screening and diagnostic procedure for cervical abnormalities. Among pre-malignant and malignant lesions, histo-pathological correlation increased with increased grade of severity of lesions. To the best of knowledge, this is the largest study of liquid based cytology in the Western Rajasthan.

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A study of cytological pattern of cervical papanicolaou smears in western Rajasthan, India

Cited by 8 publications

References 9 publications

Cytomorphological spectrum of cervical smears in a tertiary hospital

Cytomorphological spectrum of cervical smears in a tertiary hospital

Study of cytological pattern of pap smears and detection of cervical cancers in Gujarat, India

A prospective study of cervical lesions diagnosed by liquid based cytology in Western Rajasthan, India population

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