A study of clinical patterns in benign breast disorders

Abstract

Background: This is a prospective study aimed at evaluating patients presenting with breast related complaints at Dr. D.Y. Patil Medical College, Pimpri, Pune. It outlines various clinical patterns in benign breast disorders; this includes age, type of presentation, side and quadrant of breast involved, size of breast lump and the eventual diagnosis.Methods: A prospective study was conducted at Dr. D.Y. Patil Medical College, Pimpri, Pune, between July 2016 and July 2017. Author evaluated 50 patients, male and female, of all ages, presenting with complaints suggestive of a benign breast disorder. Patients that were a proven case of carcinoma of breast and those diagnosed with a malignant condition of the breast during evaluation were excluded from the study.Results: The incidence of benign breast disorders is the highest in the age group of 21 to 30 years (42%). Most common presentation of benign breast disorder in the series was found to be lump in the breast (58%). The Left breast (44%) was noted to be more commonly involved than the Right breast (40%). Most commonly involved quadrant of breast was the upper inner quadrant (30%), followed by the upper outer quadrant (24%).Most of the breast lumps were of size ranging from 3 to 3.9cm (36.58%) followed by those of size ranging from 2 to 2.9cm. (21.95%). Fibroadenoma (42%) was the most common benign breast disorder in present study, followed by fibro-adenosis (18%).Conclusions: Every benign breast disorder presents in a certain age group and follows a certain clinical pattern as outlined in this study. Detailed history taking and clinical examination while keeping in mind these clinical patterns, along with ultrasound and FNAC (triple test), aids in establishing the diagnosis of a benign breast disorder within 72 hours. Hence, the anxiety caused by breast lumps and nodularity can be alleviated by excluding the diagnosis of carcinoma breast. And since majority of benign lesions are not associated with an increased risk for subsequent breast cancer, unnecessary surgical procedures can be avoided.

Clinicopathological Evaluation of Benign Breast Disorders in Different Age Groupsa Single Centre Study

“…[4][5][6][7] In the present study, lump in the breast was the most common presentation in 60% of patients, of which more than half patients had a lump with pain; however, 12 patients presented with only pain with no other signs and symptoms, and five male patients presented with gynecomastia. These results were generally similar to previous studies where the presenting symptom was lump in the breast in 58% (Tonape et al), [8] 58.06% (Singh et al), [9] 72.35% (Ratanachaikanont et al), [10] and 87.4% (Foncroft et al). [11] In the present study, benign breast diseases was the highest in the age group of 21 to 30 years (43.08%), which was consistent with previous study by Tonape et al (42%) [8] and Das et al (45%), [12] however, in another study by Kapur et al, the highest number of benign breast diseases were found in age group of 31 to 40 years (31.6%), followed by 21 to 30 years (31.1%) and 11 to 20 years (27.3%).…”

“…These results were generally similar to previous studies where the presenting symptom was lump in the breast in 58% (Tonape et al), [8] 58.06% (Singh et al), [9] 72.35% (Ratanachaikanont et al), [10] and 87.4% (Foncroft et al). [11] In the present study, benign breast diseases was the highest in the age group of 21 to 30 years (43.08%), which was consistent with previous study by Tonape et al (42%) [8] and Das et al (45%), [12] however, in another study by Kapur et al, the highest number of benign breast diseases were found in age group of 31 to 40 years (31.6%), followed by 21 to 30 years (31.1%) and 11 to 20 years (27.3%). [13] In another study by Singh et al, aberrations in normal development and involution of the breast were highest reported in the age group 21 to 30 years and 31 to 40 years (36.36% each) and breast lump was highest reported in 21 to 30 years group (52.77%).…”

“…[14] When the location of the affected breast area was evaluated, the upper inner quadrant of the breast was found to be more (41.54%) affected. In the previous report by Tonape et al, around 30% of patients had upper inner quadrant affected; [8] however, in another report by Singh et al, upper outer quadrant was more affected (27.42%). [9] Overall, in the present study, the right side of the breast was more affected (53.85%) and was consistent with the report by Singh et al (54.84%).…”

“…[16,17] In the present study, there were five (7.69%) cases of gynecomastia, of which one case had bilateral gynecomastia. In the previous study by Bagale et al, 11 cases (2.25%) [7] were reported, other reports by Kapur et al (1%) [13] and Tonape et al (8%) [8] had different results.…”

Breast Cancer in Thi-Qar 2018, it's determinants, histopathological presentation and six years' time trends, A comparative study

“…Breast masses have a wide diversity of etiologies, commonly benign cause, fibrocystic changes are the most common breast disorder, while fibro adenoma is the most common benign breast mass; invasive ductal carcinoma is the most common malignancy (Gaaib et al, 2014;Tonape et al, 2018). The risk of breast cancer rises with age.…”