A Study of Certain Contributory Factors in the Development of Vitiligo in South Indian Patients

Levai, Marian

doi:10.1001/archderm.1958.01560090080017

Cited by 33 publications

(16 citation statements)

References 10 publications

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“…7 As an important feature of complex diseases, the age of disease onset has routinely been analyzed in association studies. 26 The mean ages of onset of vitiligo that we observed were almost identical to those found in most, [27][28][29] but not all, 30 previous studies. Patients with segmental vitiligo and a negative family history were afflicted at about age 15 years, the same as described by Hann and Lee.…”

Section: Discussionsupporting

confidence: 87%

Characteristics of genetic epidemiology and genetic models for vitiligo

Zhang

Liu

Gui

et al. 2004

Journal of the American Academy of Dermatology

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Section: Discussionsupporting

confidence: 87%

Characteristics of genetic epidemiology and genetic models for vitiligo

Zhang

Liu

Gui

et al. 2004

Journal of the American Academy of Dermatology

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“…Data on late onset vitiligo is almost nonexistent, with only a passing reference in these studies. Vitiligo is common in India, having a prevalence ranging from 0.46% to 8.8% 8–13 . From a total of 2672 vitiligo patients, 182 (6.8%) were elderly (> 50 years).…”

Section: Discussionmentioning

confidence: 99%

Late onset vitiligo: A study of 182 patients

et al. 2004

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The elderly constitute a large and rapidly growing segment of the population; however, there is complete lack of information about the epidemiology of vitiligo in this age group. To study the clinical and epidemiological profile of vitiligo in the elderly, we retrospectively analyzed the data of patients with vitiligo having onset of disease after 50 years of age attending the pigmentary clinic of our center. Of the 182 patients, 87 (47.8%) were males and 95 (52.2%) were females. The mean age of onset of disease was 55 +/- 2.3 years. Vitiligo vulgaris was the most common (83.5%) followed by focal (5.5%), segmental (4.4%), acrofacial (3.8%), mucosal (2.2%), and universal (0.5%). The most common site of onset was the head and neck (24.2%) followed by the upper limbs (23%), trunk (22%), lower limbs (17.6%), oral/genital mucosae (7.1%), and flexures (6%). Koebner's phenomenon was observed in 14.8% while leukotrichia was present in 47.3% of the patients. Halo nevi were observed in 3.8% of patients, and vitiligo was stable in 64.8%. Twenty-nine (15.9%) patients had family history of vitiligo. Associated autoimmune autoimmune/endocrine disorders were present in 39 (21.4%) of the patients. Differences in disease characteristics compared with vitiligo in children and young adults are discussed.

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“…Both members of monozygotic twin pairs have also been found to be affected [Mohr, 1951;Siemens, 19531. Positive family history of vitiligo has been noted in many studies [Mehta et al, 1973;Lerner, 1959;Behl, 1955;Levai, 1958;Goudie et al, 1980;Cockayne, 19331. The mode of inheritance of the disease is still debated.…”

Section: Introductionmentioning

confidence: 98%

Studies on vitiligo I. Epidemiological profile in Calcutta, India

Das

Majumder

Chakrabotry

et al. 1985

Genetic Epidemiology

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An epidemiological profile of vitiligo in Calcutta is presented. Prevalence data were gathered from 15,685 individuals drawn from the general population; pedigree data were collected through 293 vitiligo patients. The overall prevalence of vitiligo is about 5 per 1,000 individuals. There are no significant sex or age differences in prevalence rates. About a 4.5-fold increase in prevalence is observed among close biological relatives of affected individuals. There is, however, no clearcut correspondence between relative risks and kinship coefficients. There are no significant differences in the frequencies of various types of vitiligo between probands with and without positive family history. The overall mean and modal ages of onset are about 22 years and 15 years, respectively. The mean ages among males (24.8 years) and females (19.3 years) are significantly different.

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A Study of Certain Contributory Factors in the Development of Vitiligo in South Indian Patients

Cited by 33 publications

References 10 publications

Characteristics of genetic epidemiology and genetic models for vitiligo

Characteristics of genetic epidemiology and genetic models for vitiligo

Late onset vitiligo: A study of 182 patients

Studies on vitiligo I. Epidemiological profile in Calcutta, India

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