A Study Comparing SPECT and MRI in Patients With Anosmia After Traumatic Brain Injury

Mann, Norman M.; Vento, John A.

doi:10.1097/01.rlu.0000227010.72925.6d

Cited by 18 publications

(13 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Bland de 66 studerade patienterna indelade i grupper efter svårighetsgrad av smakförändring, hade de med svåra smakförändringar ett minskat näringsintag med 1000 -900 kcal/dag jämfört med de utan smakförändringar. SoL-förändringar kan också förekomma vid andra sjukdomar såsom Alzheimers sjukdom (114) och hjärnskador (32,73). Många mediciner har SoL-förändringar som biverkning (2,28,30).…”

Section: Faktorer Som Kan Påverka Smak-och Luktförmåganunclassified

Taste and Smell Changes in Patients Receiving Cancer Chemotherapy

2009

View full text Add to dashboard Cite

Few studies have described how patients receiving chemotherapy experience taste/smell changes (TSCs). Food and meal situations have important meaning beyond nutrition, so these common symptoms may affect daily lives. This study aims to investigate distress and impact on daily life from TSCs in patients receiving cancer chemotherapy, analyze reported levels of distress and impact on daily life from TSCs with regard to sociodemographic and clinical factors, and explore patients' reports of self-care strategies and communication with staff. The 340 patients reporting TSCs on a multicenter survey (n = 518) were grouped into subsets by level of TSC-related distress and impact on daily life, which served as the basis for statistical comparison. Written comments were analyzed inductively using content analysis. Nearly one-third of participating patients reported both high levels of distress and impact on daily life (high distress and high impact on daily life [HDHI]) from TSCs. The HDHI subset reported other symptoms more often than others did (P = .01) and also more often responded to open questions about distress, impact, and self-care strategies (P = .01). Taste/smell changes were not always reported to staff, even in the HDHI subset. The specific aspects of TSCs resulting in distress and impact on daily life varied greatly, affecting both psychological and somatic aspects, with little consensus and great individual differences described in self-care strategies. The variety of distress, impact, and strategies used to alleviate TSCs clarifies the importance of situational meaning.

show abstract

Section: Faktorer Som Kan Påverka Smak-och Luktförmåganunclassified

Taste and Smell Changes in Patients Receiving Cancer Chemotherapy

2009

View full text Add to dashboard Cite

show abstract

“…Nevertheless, the dispersed nature of the olfactory system within cortical and subcortical regions facilitates the fact that traumatic lesions involve, at least in part, the areas concerned with olfactory processing. Evidence from neuroimaging studies indicate that a damage at the level of eminent olfactory regions, such as entorhinal cortex or orbitofrontal cortex, is associated with poor performances at olfactory behavioral tasks (Atighechi, Salari, Baradarantar, Jafari, Karimi, & Mirjali, 2009;Bonanni et al, 2006;Fujiwara, Schwartz, Gao, Black, & Levine, 2008;Geisler, Schlotfeldt, Middleton, Dulay, & Murphy, 1999;Haxel, Grant, & Mackay-Sim, 2008;Mann & Vento, 2006;Roberts, Sheehan, Thurber, & Roberts, 2010;Sandford et al, 2006;Yousem, Geckle, Bilker, McKeown, & Doty, 1996). It must be said, however, that the present bulk of studies, as well as those only considering patients' performance at olfactory psychophysical tests (Callahan & Hinkebein, 1999De Kruiijk et al, 2003;Fortin, Lefebvre, & Ptito, 2010;Green & Iverson, 2001;Green, Rohling, Iverson, & Gervais, 2003;Landis et al, 2010;Sigurdardottir, Jerstad, Andelic, Roe, & Schanke, 2010;Swann, Bauza-Rodriguez, Currans, Riley, & Shukla, 2006), applied testing methods that require some specific cognitive functions to be intact.…”

Section: Introductionmentioning

confidence: 94%

Implicit olfactory abilities in traumatic brain injured patients

Parma

Straulino

Zanatto

et al. 2012

Journal of Clinical and Experimental Neuropsychology

View full text Add to dashboard Cite

To investigate implicit olfactory abilities in a group of anosmic traumatic brain injured (TBI) patients, an olfactomotor priming paradigm was administered. A group of matched normosmic/mildly microsmic TBI patients and a group of neurologically healthy participants served as controls. For all the groups, an interference effect was evident on the peak velocity of grip aperture when participants grasped a large target preceded by a "small" odor. The present results suggest that some form of implicit olfactory processing is preserved in TBI patients even when diagnosed as anosmic on the basis of explicit olfactory testing.

show abstract

“…Often, these changes in blood flow are invisible to CT and MRI. [95][96][97][98] This makes HMPAO-SPECT a valuable adjunct imaging modality when FDG-PET cannot be obtained, especially if the clinician is suspicious of a brain injury for which there is no clear anatomical etiology.…”

Section: Spect: Widely Available and Often Underutilizedmentioning

confidence: 99%

Neuroimaging of Traumatic Brain Injury

Dubroff

Newberg²

2008

Semin Neurol

View full text Add to dashboard Cite

Head trauma requires several different neuroimaging modalities for adequate evaluation and determination of treatment. This article considers the importance of anatomical and functional imaging modalities in the initial evaluation, treatment planning, and long-term management of patients with head injury. These modalities include computed tomography, magnetic resonance imaging, positron emission tomography, and single photon emission computed tomography. Each modality offers specific advantages and potential disadvantages. However, it is important to understand the capabilities of each modality, and how and when each one might provide the most valuable information as one evaluates such patients.

show abstract

A Study Comparing SPECT and MRI in Patients With Anosmia After Traumatic Brain Injury

Abstract: This study identified altered blood perfusion pattern in otherwise normal anatomic structures on MRI.

Cited by 18 publications

References 9 publications

Taste and Smell Changes in Patients Receiving Cancer Chemotherapy

Taste and Smell Changes in Patients Receiving Cancer Chemotherapy

Implicit olfactory abilities in traumatic brain injured patients

Neuroimaging of Traumatic Brain Injury

Contact Info

Product

Resources

About