A Special Cannula for Determination of Blood Flow in the Left Common Coronary Artery of the Dog

Eckstein, Richard W.; McEachen, James A.; Demming, J.; Newberry, William

doi:10.1126/science.113.2936.385

Cited by 11 publications

(2 citation statements)

References 5 publications

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“…The common left coronary is too short to allow the application of a flow transducer ( Fig. 1), so we used a modified cannulation technique (Chamibliss, Demming, Wells, Cline & Eckstein, 1950;Eckstein, McEachen, Denning & Newberry, 1951). A stainless steel cannula with an internal diameter of 3 mm was inserted through the left su'bclavian artery, round the aortic arch and into the root of the left coronary artery, where it was tied in place with a ligature round the outside of the artery.…”

Section: Methodsmentioning

confidence: 99%

The effects of pronethalol and propranolol on the coronary circulation of the dog

Davis

MacDonald

Mason

1969

British J Pharmacology

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1. The actions of pronethalol and propranolol have been studied to see if there was any relationship between the reduction in coronary flow and any other cardiovascular action they have. 2. The experiments were carried out in anaesthetized open chest dogs. Measurements included central arterial, left and right venous or atrial pressures, heart rate, ventricular size and stroke volume, intra-ventricular pressures, total left coronary flow, arterial and coronary sinus blood p02. The pressure-time index (PTI) and maximum rate of isovolumetric contraction (dp/dt) were obtained from these records. 3. It was concluded that, in these experiments, the reduction in coronary flow produced by pronethalol and propranolol was not directly related to a decrease in perfusion pressure, a raised venous pressure, the increase in ventricular volume and hence wall tension, the decrease in heart rate, or to the increased duration of systole. 4. The PTI and dp/dt were always reduced at the same time as the coronary flow. These findings are discussed. 5. Studies of the effects of sympathetic stimulation, of phentolamine, of reduced arterial oxygen tension and electrical pacing of the heart, all after ,/-blockade, did not support the suggestion that the reduction in coronary flow after 8-blockade was due to the unmasking of an active vasoconstriction.

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Section: Methodsmentioning

confidence: 99%

The effects of pronethalol and propranolol on the coronary circulation of the dog

Davis

MacDonald

Mason

1969

British J Pharmacology

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“…The common left artery was eannulated via the subclavian artery either with the special compi-ession eannula 6 or with a cannula ligated in place. Both arteries were perfused with blood brought from the aorta through a metal sound introduced via the left common carotid artery or from a pressure chamber as described above.…”

Section: Mean Septal Arterial Inflowmentioning

confidence: 99%

Phasic and Mean Blood Flow in the Canine Septal Artery and an Estimate of Systolic Resistance in Deep Myocardial Vessels

Eckstein

Moir

Driscol

1963

Circulation Research

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Methods SURGICAL PREPARATIONMongrel dogs weighing from 15 to 22 kg were anesthetized with 30 rag of morphine and 25 to 30 mg/kg of sodium pentobarbital. Respiration was provided through an intratracheal tube with room air under intermittent positive pressure. The left chest was opened between the 4th and 5th ribs and the septal artery was isolated. In three in-203 at University of Edinburgh (edu) / Scotland on June 12, 2015 http://circres.ahajournals.org/ Downloaded from at University of Edinburgh (edu) / Scotland on June 12, 2015 http://circres.ahajournals.org/ Downloaded from MP C5 K, to •-3 M at University of Edinburgh (edu) / Scotland on June 12, 2015

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Methoden zur Gewinnung und Gasanalyse von Gas- und Blutproben

Bartels¹,

Bücherl²,

Hertz³

et al. 1959

Lungenfunktionsprüfungen

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A Special Cannula for Determination of Blood Flow in the Left Common Coronary Artery of the Dog

Cited by 11 publications

References 5 publications

The effects of pronethalol and propranolol on the coronary circulation of the dog

The effects of pronethalol and propranolol on the coronary circulation of the dog

Phasic and Mean Blood Flow in the Canine Septal Artery and an Estimate of Systolic Resistance in Deep Myocardial Vessels

Methoden zur Gewinnung und Gasanalyse von Gas- und Blutproben

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